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Blockade of the cholecystokinin CCK-2 receptor prevents the normalization of anxiety levels in the rat
ArticleAbstract: Cholecystokinin (CCK), through the CCK-2 receptor, exerts complex effects on anxiety. While CCK agonPalabras claves:Behavior rating scale, Cholecystokinin, Cholecystokinin B, Performance anxiety, ReceptorAutores:Akil H., Bourin M., Santiago J. Ballaz, Watson S.J.Fuentes:googlescopusAnti-Inflammatory Therapy as a Promising Target in Neuropsychiatric Disorders
Book PartAbstract: This chapter analyzes the therapeutic potential of current anti-inflammatory drugs in treating psychPalabras claves:anti-inflammatory agents, cytokines, glucocorticoids, inflammation, Mental Disorders, PsychoneuroimmunologyAutores:Bourin M., Santiago J. BallazFuentes:googlescopus2,5-Diketopiperidine derivatives as non-peptide ligands for cholecystokinin receptors
ArticleAbstract: Easily accessible 2,5-diketopiperidines have been used as templates for the construction of Trp-PhePalabras claves:Autores:Del Río J., Dominguez M.J., Fortuno A., Garcı́a-López M.T., Gonzalez-Muniz R., Herranz R., Santiago J. BallazFuentes:googlescopus2-Oxopyrrolidines and 6-oxoperhydropyrrolo[1,2-a]pyrazines as templates in the search for nonpeptide cholecystokinin ligands
ArticleAbstract: In order to find new classes of non-peptide cholecystokinin (CCK) ligands, the conformational restriPalabras claves:2-Oxopyrrolidine, Cholecystokinin mimetic, Perhydropyrrolo[1,2-a]pyrazineAutores:Cenarruzabeitia E., Del Río J., Garcı́a-López M.T., Gonzalez-Muniz R., Herranz R., LaTorre M., Martín-Martínez M., Santiago J. BallazFuentes:googlescopus5-(Tryptophyl)amino-1,3-dioxoperhydropyrido[1,2-c]pyrimidine-based potent and selective CCK<inf>1</inf> receptor antagonists: Structural modifications at the tryptophan domain
ArticleAbstract: Analogues of the previously reported potent and highly selective CCK1 receptor antagonist (4aS,5R)-2Palabras claves:Autores:Bartolomé-Nebreda J.M., Cenarruzabeitia E., Del Río J., Garcı́a-López M.T., Gómez-Monterrey I., Gonzalez-Muniz R., Herranz R., LaTorre M., Martín-Martínez M., Santiago J. BallazFuentes:scopusAscorbate prevents cell death from prolonged exposure to glutamate in an in vitro model of human dopaminergic neurons
ArticleAbstract: Ascorbate (vitamin C) is a nonenzymatic antioxidant highly concentrated in the brain. In addition toPalabras claves:AMPA receptor, Glutamate metabotropic receptors, Kainate receptor, NMDA receptor, Parkinson's Disease, SH-SY5YAutores:Morales I., Obeso J.A., Rodriguez M., Santiago J. BallazFuentes:googlescopusFacilitation by 8-OH-DPAT of passive avoidance performance in rats after inactivation of 5-HT(1A) receptors
ArticleAbstract: 1. Pretraining administration of 8-hydroxy-2-di-n-propylamino-tetralin (8-OH-DPAT 0.1 mg kg-1), a 5-Palabras claves:5-HT(1A) receptors, 8-OH-DPAT, EEDQ, hippocampus, Passive avoidanceAutores:Del Río J., Frechilla D., García-Osta A., Otano A., Santiago J. BallazFuentes:googlescopusDoes endogenous cholecystokinin modulate alcohol intake?
ReviewAbstract: Alcohol use disorder or alcoholism is characterized by uncontrollable alcohol use and intoxication,Palabras claves:5-Hydroxytryptamine-3 receptor, Alcoholism, Cholecystokinin, Gamma-aminobutyric acid, orexin, oxytocinAutores:Bourin M., Nicole Espinosa, Santiago J. BallazFuentes:googlescopusNeurocytotoxicity of imidacloprid- and acetamiprid-based comercial insecticides over the differentiation of SH-SY5Y neuroblastoma cells
ArticleAbstract: Neonicotinoids are effective insecticides with specificity for invertebrate nicotinic acetylcholinePalabras claves:cell differentiation, Cell survival, Neonicotinoids, Neurons, Oxidative Stress, ToxicityAutores:Aguayo L.G., Guzmán-Vallejos M.S., Lenin Javier Ramírez Cando, Santiago J. Ballaz, Vera-Erazo F.D.Fuentes:googlescopusMDMA ('Ecstasy') enhances 5-HT(1A) receptor density and 8-OH-DPAT- induced hypothermia: Blockade by drugs preventing 5-hydroxytryptamine depletion
ArticleAbstract: One week after a single administration of 3,4- methylenedioxymethamphetamine (MDMA · HCl, 30 mg/kg iPalabras claves:5-HT (serotonin, 5- hydroxytryptamine), 5-HT(1A) receptor, 8-OH-DPAT (8-hydroxy-2-(di-n- propylamino)tetralin), MDMA (3,4-methylenedioxymethamphetamine), TEMPERATUREAutores:Aguirre N., Del Río J., Lasheras B., Santiago J. BallazFuentes:googlescopus