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Characterization of Saccharomyces cerevisiae Nop17p, a Novel Nop58p-interacting protein that is involved in Pre-rRNA processing
ArticleAbstract: In eukaryotes, pre-rRNA processing depends on cis-acting elements and on a large number of non-ribosPalabras claves:protein-protein interactions, rRNA processing, S. cerevisiae, snoRNPAutores:Fernando A. Gonzales-Zubiate, Luz J.S., Oliveira C.C., Zanchin N.I.T.Fuentes:googlescopusAnalysis of the Saccharomyces cerevisiae exosome architecture and of the RNA binding activity of Rrp40p
ArticleAbstract: The exosome is a complex of eleven subunits in yeast, involved in RNA processing and degradation. DePalabras claves:exosome, Protein-protein interaction, RNA binding, RNaseAutores:Fernando A. Gonzales-Zubiate, Luz J.S., Oliveira C.C., Santos M., Tavares J.Fuentes:googlescopusA mutation in human VAP-B-MSP domain, present in ALS patients, affects the interaction with other cellular proteins
ArticleAbstract: Amyotrophic Lateral Sclerosis (ALS) is the most common adult-onset Motor Neuron Disease (MND), charaPalabras claves:amyotrophic lateral sclerosis, dimerization, Protein interaction, VAP-BAutores:Fernando A. Gonzales-Zubiate, Luz J.S., Mitne-Neto M., Nishimura A., Oliveira C.C., Pimenta D.C., Ramos C., Zatz M.Fuentes:googlescopusA protein folding robot driven by a self-taught agent
ArticleAbstract: This paper presents a computer simulation of a virtual robot that behaves as a peptide chain of thePalabras claves:CORONAVIRUS, Protein folding, reinforcement learning, Self-taught agentsAutores:Antonio Díaz-Barrios, Fernando A. Gonzales-Zubiate, Israel Pineda, Luis Zhinin-Vera, Oscar Chang, Rafael Valencia-RamosFuentes:googlescopusMutational analysis of the yeast RNA helicase Sub2p reveals conserved domains required for growth, mRNA export, and genomic stability
ArticleAbstract: Sub2p/UAP56 is a highly conserved DEAD-box RNA helicase involved in the packaging and nuclear exportPalabras claves:genome stability, RNA, RNA export, RNA helicaseAutores:Brodersen D.E., Bøggild A., Fernando A. Gonzales-Zubiate, Jankowsky E., Jensen T.H., Latrick C.M., Malagon F., Putnam A., Saguez C., Sanderson L., Schmid M.Fuentes:googlescopusNop17 is a key R2TP factor for the assembly and maturation of box C/D snoRNP complex
ArticleAbstract: Background: Box C/D snoRNPs are responsible for rRNA methylation and processing, and are formed by sPalabras claves:box C/D snoRNP assembly, Nop17, R TP complex 2Autores:Fernando A. Gonzales-Zubiate, Georg R., Luz J.S., Oliveira C.C., Prieto M.Fuentes:googlescopusNop53p, an essential nucleolar protein that interacts with Nop17p and Nip7p, is required for pre-rRNA processing in Saccharomyces cerevisiae
ArticleAbstract: In eukaryotes, pre-rRNA processing depends on a large number of non-ribosomal trans-acting factors tPalabras claves:NUCLEOLUS, pre60s, Ribosome synthesis, rRNA processing, Saccharomyces CerevisiaeAutores:Cassiola F., Fernando A. Gonzales-Zubiate, Granato D., Luz J.S., Machado-Santelli G., Oliveira C.C.Fuentes:googlescopusNucleolar localization of the yeast RNA exosome subunit Rrp44 hints at early pre-rRNA processing as its main function
ArticleAbstract: The RNA exosome is a multisubunit protein complex involved in RNA surveillance of all classes of RNAPalabras claves:Autores:Fernando A. Gonzales-Zubiate, Gadal O., Okuda E.K., Oliveira C.C.Fuentes:googlescopusMechanisms of nuclear transport in the cell: RNA exosome in saccharomyces cerevisiae
ReviewAbstract: Ribonucleases (RNases) functions in the cell include precise maturation of non- coding RNAs and degrPalabras claves:exosome, Nuclear transport, Ribonucleases, RNA degradation, RNA processing, Rrp44, Rrp6Autores:Fernando A. Gonzales-Zubiate, Rech B.Fuentes:googlescopusInhibition of cyclin-dependent kinase CDK1 by oxindolimine ligands and corresponding copper and zinc complexes
ArticleAbstract: Oxindolimine-copper(II) and zinc(II) complexes that previously have shown to induce apoptosis, withPalabras claves:Cytotoxicity mechanism, Kinase inhibitors, Molecular docking, molecular dynamics, Oxindolimine-metal complexesAutores:Da Costa Ferreira A.M., Do Nascimento R.R., Fernando A. Gonzales-Zubiate, Kumar N., Miguel R.B., Oliveira C.C., Petersen P.A.D., Petrilli H.M.Fuentes:googlescopus