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Characterization of epitopes on human interleukin-2 using phage displayed-peptide libraries: Insights into antibody-peptide interactions
ArticleAbstract: We have characterized the binding epitopes of two monoclonal antibodies (MAbs) reacting with human IPalabras claves:Autores:Araña M.J., Cesareni G., Chinea G., Ojalvo A.G., Santiago Nelson VispoFuentes:scopusA theoretical and experimental study on the potential luminescent and biological activities of diaminodicyanoquinodimethane derivatives
ArticleAbstract: Recently, several studies have demonstrated that diaminodicyanoquinone derivatives (DADQs) could prePalabras claves:Fluorescence, Luminescence, quantum yield, Quinones, TD-DFTAutores:Edison Rafael Jiménez, Fernando Javier Torres, Hortensia Rodriguez Cabrera, Manuel Caetano, Santiago Nelson Vispo, Terencio T.Fuentes:scopusGangliosides, Ab1 and Ab2 antibodies. I. Towards a molecular dissection of an idiotype-anti-idiotype system
ArticleAbstract: This report is focused on the molecular basis for the interaction of a monoclonal antibody (mAb) andPalabras claves:Anti-idiotypic antibodies, H-CDR, N-Glycolyl-gangliosidesAutores:González M., López-Requena A., Mateo de Acosta C., Moreno E., Pérez R., Puchades Y., Santiago Nelson Vispo, Talavera A., Vázquez A.M.Fuentes:scopusExpression and Characterization of Human Vascular Endothelial Growth Factor Produced in SiHa Cells Transduced with Adenoviral Vector
ArticleAbstract: The vascular endothelial growth factor (VEGF) is an essential factor to pathologic angiogenesis. DisPalabras claves:Adenoviral vector, ECV-304 cells, HUVEC, Vascular permeability, VEGF 121Autores:Aedo G., Camacho F., Castillo C., González-Chavarría I., González-Horta E.E., Mansilla R., Parra N.C., Sanchez O., Santiago Nelson VispoFuentes:scopusExpression and folding of an interleukin-2-proinsulin fusion protein and its conversion into insulin by a single step enzymatic removal of the C-peptide and the N-terminal fused sequence
ArticleAbstract: We report the expression in E. coli of a proinsulin fusion protein carrying a modified interleukin-2Palabras claves:Enzymatic processing, Proinsulin folding, Recombinant insulinAutores:Besada-Pérez V., Castellanos‐Serra L., Eugenio Hardy, Falcón-Cama V., Fernandez C., Gonzalez M., Herrera L., Perez G., Santiago Nelson Vispo, Santos-Savio A., Silva A., Ubieta R.Fuentes:scopusExpression of il-2/proinsulin fusion protein: Folding of the fusion protein and conversion into insulin by a one step removal of c-peptide and leader sequence
ArticleAbstract:Palabras claves:Autores:Besada-Pérez V., Castellanos L.R., Estrada R., Eugenio Hardy, Fernandez C., Gonzalez M., Herrera L., Jimenez V., Perez G., Santiago Nelson Vispo, Silva A., Ubieta R.Fuentes:scopusNovel Tyrosine Markers in Raman Spectra of Wild-Type and Mutant (Y21M and Y24M) Ff Virions Indicate Unusual Environments for Coat Protein Phenoxyls
ArticleAbstract: The tyrosine side chain generates a pair of distinctive Raman bands—a Fermi doublet near 850 and 830Palabras claves:Autores:Aubrey K.L., Cesareni G., Overman S.A., Santiago Nelson Vispo, Thomas G.J.Fuentes:scopusGrowth-hormone-releasing peptide 6 (GHRP6) prevents oxidant cytotoxicity and reduces myocardial necrosis in a model of acute myocardial infarction
ArticleAbstract: Therapies aimed at enhancing cardiomyocyte survival following myocardial injury are urgently requirePalabras claves:Cardioprotection, Growth-hormone-releasing peptide 6 (GHRP6), infarction, Ischaemia, myocardium, Necrosis, Oxidative StressAutores:Alba J., Berlanga-Acosta J., Cibrian D., Dominguez H., Garcia D., Guevara L., Guillén-Nieto G.E., López-Mola E., López-Saura P.A., Perez B., Rodriguez A., Santiago Nelson Vispo, Seralena A.Fuentes:scopusMarine Arthropods as a Source of Antimicrobial Peptides
ReviewAbstract: Peptide therapeutics play a key role in the development of new medical treatments. The traditional fPalabras claves:AMP, Antimicrobial peptides, Crustaceans, defense system, drug, SHRIMPAutores:Alberício F., Fernando Gushque, Frank Alexis, Jenny Rodriguez, Juan Pablo Saucedo-Vázquez, Marco Esteban Gudiño Gomezjurado, Santiago Nelson Vispo, Tellkamp M.P.Fuentes:scopusPreferential selection of Cys-constrained peptides from a random phage-displayed library by anti-glucitollysine antibodies
ArticleAbstract: Phage-displayed peptides recognized by two monoclonal antibodies against glucitollysine were selectePalabras claves:Disulfide bridges, Glucitollysine, Peptide library, phage displayAutores:Del Rosario Aleman M., Pupo A., Rojas G., Santiago Nelson VispoFuentes:scopus