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Characterization of epitopes on human interleukin-2 using phage displayed-peptide libraries: Insights into antibody-peptide interactions
ArticleAbstract: We have characterized the binding epitopes of two monoclonal antibodies (MAbs) reacting with human IPalabras claves:Autores:Araña M.J., Cesareni G., Chinea G., Ojalvo A.G., Santiago Nelson VispoFuentes:scopusBiotechnology
OtherAbstract:Palabras claves:Autores:Santiago Nelson VispoFuentes:scopusAntitumor effect of a novel proapoptotic peptide that impairs the phosphorylation by the protein kinase 2 (casein kinase 2)
ArticleAbstract: Protein Kinase (casein kinase 2, CK2) is a serine-threonine kinase that is frequently dysregulated iPalabras claves:Autores:Acevedo B.E., Alonso D.F., Falcón-Cama V., López-Mola E., Mendoza O., Perea-Rodríguez S.E., Puchades Y., Reyes O., Santiago Nelson Vispo, Santos-Savio A., Silva R., Torrens I.Fuentes:scopusCRISPR-Cas9: A Precise Approach to Genome Engineering
ArticleAbstract: In the last few decades, genomic manipulation has made significant progress as a result of the develPalabras claves:bacterial adaptive defense system, clinical trials, CRISPR-Cas9, genetic engineering, NGSAutores:Jorge E. Simón, Rodríguez Á.S., Santiago Nelson VispoFuentes:scopusGangliosides, Ab1 and Ab2 antibodies. I. Towards a molecular dissection of an idiotype-anti-idiotype system
ArticleAbstract: This report is focused on the molecular basis for the interaction of a monoclonal antibody (mAb) andPalabras claves:Anti-idiotypic antibodies, H-CDR, N-Glycolyl-gangliosidesAutores:González M., López-Requena A., Mateo de Acosta C., Moreno E., Pérez R., Puchades Y., Santiago Nelson Vispo, Talavera A., Vázquez A.M.Fuentes:scopusExpression and Characterization of Human Vascular Endothelial Growth Factor Produced in SiHa Cells Transduced with Adenoviral Vector
ArticleAbstract: The vascular endothelial growth factor (VEGF) is an essential factor to pathologic angiogenesis. DisPalabras claves:Adenoviral vector, ECV-304 cells, HUVEC, Vascular permeability, VEGF 121Autores:Aedo G., Camacho F., Castillo C., González-Chavarría I., González-Horta E.E., Mansilla R., Parra N.C., Sanchez O., Santiago Nelson VispoFuentes:scopusExpression and folding of an interleukin-2-proinsulin fusion protein and its conversion into insulin by a single step enzymatic removal of the C-peptide and the N-terminal fused sequence
ArticleAbstract: We report the expression in E. coli of a proinsulin fusion protein carrying a modified interleukin-2Palabras claves:Enzymatic processing, Proinsulin folding, Recombinant insulinAutores:Besada-Pérez V., Castellanos‐Serra L., Eugenio Hardy, Falcón-Cama V., Fernandez C., Gonzalez M., Herrera L., Perez G., Santiago Nelson Vispo, Santos-Savio A., Silva A., Ubieta R.Fuentes:scopusHybrid Rop-pIII proteins for the display of constrained peptides on filamentous phage capsids
Conference ObjectAbstract: In order to increase the versatility of phage display technology, it is desirable to be able to impoPalabras claves:Peptides, phageAutores:Castagnoli L., Cesareni G., Felici F., Santiago Nelson VispoFuentes:scopusPeptide Phage Display: Molecular Principles and Biomedical Applications
ReviewAbstract: Phage display (PD) is a technology based on the presentation of functional exogenous peptides on thePalabras claves:Cáncer, clinical trials, Drug delivery system, infection diseases, peptide libraries, phage displayAutores:Karen Elizabeth Sánchez Blacio, Marlon S. Zambrano-Mila, Santiago Nelson VispoFuentes:scopusSelection from a peptide library of the antigenic determinants of a protein.
ReviewAbstract:Palabras claves:Autores:Castagnoli L., Cesareni G., Felici F., Gonfloni S., Santiago Nelson Vispo, Vetriani C.Fuentes:scopus