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Chemical Conjugation in Drug Delivery Systems
ReviewAbstract: Cancer is one of the diseases with the highest mortality rate. Treatments to mitigate cancer are usuPalabras claves:Biomolecules, Carriers, covalent bioconjugation, Drug delivery systems, linkersAutores:Alberício F., Alexis Eras, Danna Castillo, Hortensia Rodriguez Cabrera, Santiago Nelson Vispo, Suárez Navarro M.Fuentes:scopusCharacterization of epitopes on human interleukin-2 using phage displayed-peptide libraries: Insights into antibody-peptide interactions
ArticleAbstract: We have characterized the binding epitopes of two monoclonal antibodies (MAbs) reacting with human IPalabras claves:Autores:Araña M.J., Cesareni G., Chinea G., Ojalvo A.G., Santiago Nelson VispoFuentes:scopusA monoclonal antibody against NeuGc-containing gangliosides contains a regulatory idiotope involved in the interaction with B and T cells
ArticleAbstract: P3 (IgM-κ) is a monoclonal antibody (mAb) reacting with N-glycolyl neuraminic acid (NeuGc)-containinPalabras claves:H-CDR3, Idiotype, Monoclonal antibody, N-Glycolyl neuraminic acidAutores:Mier E., Perez A., Rodríguez R., Santiago Nelson Vispo, Vázquez A.M.Fuentes:scopusA theoretical and experimental study on the potential luminescent and biological activities of diaminodicyanoquinodimethane derivatives
ArticleAbstract: Recently, several studies have demonstrated that diaminodicyanoquinone derivatives (DADQs) could prePalabras claves:Fluorescence, Luminescence, quantum yield, Quinones, TD-DFTAutores:Edison Rafael Jiménez, Fernando Javier Torres, Hortensia Rodriguez Cabrera, Manuel Caetano Sousa, Santiago Nelson Vispo, Terencio T.Fuentes:scopusThe race for a coronavirus vaccine
ReviewAbstract:Palabras claves:Autores:Ferbeyre G., Santiago Nelson VispoFuentes:scopusTherapeutic angiogenesis following intramuscular gene transfer of vascularendothelial growth factor 121 in a dog model of hindlimb ischemia
ArticleAbstract: Vascular endothelial growth factor (VEGF), an endothelial cell-specific mitogen, has been shown to pPalabras claves:Collateral development, Gene therapy, Naked plasmid DNA, Peripheral vascular disease, revascularizationAutores:Aldama A., Alfonso M.A., Alfredo Aldama, Alí A., Herrera L., López-Saura P.A., Montequín J.F., Ojalvo A.G., Puchades Y., Santiago Nelson Vispo, Seralena A., Seuc A., Silva R., Simón R., Sorell L.T., Vazquez R.Fuentes:scopusTherapeutics and prospects of interleukin 2
ReviewAbstract: Interleukin-2 was discovered back in 1983 as an autocrine growth factor for cultured T cells and wasPalabras claves:Cancer, hiv, immunotherapy, Interleukin-2Autores:Nicole Lovato, Santiago Nelson VispoFuentes:scopusMultilayer Nanocarrier for the Codelivery of Interferons: A Promising Strategy for Biocompatible and Long-Acting Antiviral Treatment
ArticleAbstract: Background: Interferons (IFNs) are cytokines involved in the immune response with a synergistic reguPalabras claves:Antiproliferative, antiviral, Core-shell, Drug delivery system, Immunoregulation, interferons, nanoencapsulation, toxicityAutores:Altamirano C., Debut Alexis, Felipe Sandoval, Florence Hugues, Gómez-Gaete C., Hortensia Rodriguez Cabrera, Ignacio Cabezas, Lamazares E., Leandro Santiago-Padilla, marbel torres arias, Montesino R., Parra N.C., Ramos O.S., Santiago Nelson Vispo, Sarah Martin-Solano, Thelvia I. Ramos Gómez, Toledo J.R., Viana Manrique-Suárez, Villacis-Aguirre C.A.Fuentes:scopusFrom Genetic Engineering to Preclinical Safety: A Study on Recombinant Human Interferons
ArticleAbstract: There is a critical gap in the preclinical research of recombinant human interferons (rhIFNα-2b andPalabras claves:animal model, Antiproliferative, antiviral, bioactivity, Immunomodulatory, interferon alpha, Interferon gamma, Preclinical, Recombinant, toxicityAutores:Cristy N. Culqui-Tapia, Felipe Sandoval, Ignacio Cabezas, Lamazares E., Mansilla R., María A. Contreras, Parra N.C., Sanchez O., Santiago Nelson Vispo, Sarah Martin-Solano, Sergio Donoso-Erch, Thelvia I. Ramos Gómez, Viana Manrique-Suárez, Villacis-Aguirre C.A.Fuentes:scopusThe Hitchhiker’s Guide to Human Therapeutic Nanoparticle Development
ReviewAbstract: Nanomedicine plays an essential role in developing new therapies through novel drug delivery systemsPalabras claves:clinical trials, Immunotoxicity, nanomedicine, Nanoparticles, pharmacokinetics, Preclinical, Regulatory aspectsAutores:Altamirano C., Katherine V. López-Aguilar, Santiago Nelson Vispo, Thelvia I. Ramos Gómez, Toledo J.R., Villacis-Aguirre C.A.Fuentes:scopus