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Calculating Resin Functionalization in Solid-Phase Peptide Synthesis Using a Standardized Method based on Fmoc Determination
ArticleAbstract: Solid-phase synthesis is the method of choice for peptide preparation in both research and industriaPalabras claves:Fmoc, resin functionalization, solid-phase synthesis, standardizationAutores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A.Fuentes:scopusGreen Solid-Phase Peptide Synthesis 2. 2-Methyltetrahydrofuran and Ethyl Acetate for Solid-Phase Peptide Synthesis under Green Conditions
ArticleAbstract: N,N-Dimethylformamide (DMF), N-methyl-2-pyrrolidone, and dichloromethane (DCM) are the most widely uPalabras claves:2-MeTHF, Green Chemistry, Peptide aggregation, Polyethylene glycol resins, Solid-phase peptide synthesis, solid-phase synthesisAutores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Kruger H.G.Fuentes:scopusGreen Transformation of Solid-Phase Peptide Synthesis
ReviewAbstract: Peptides play key roles in medicinal chemistry, being found in therapeutics and diagnostic agents, aPalabras claves:Green Chemistry, Green solvents, Parallel synthesis, Peptide synthesis, solid-phase synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusEDC·HCl and Potassium Salts of Oxyma and Oxyma-B as Superior Coupling Cocktails for Peptide Synthesis
ArticleAbstract: Nowadays, DIC is the most widely used carbodiimide for solid-phase peptide synthesis, while EDC·HClPalabras claves:peptide coupling, Peptides, solid-phase synthesis, Steric hindrance, synthetic methodsAutores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopusOxymaPure Coupling Reagents: Beyond Solid-Phase Peptide Synthesis
ArticleAbstract: OxymaPure [ethyl 2-cyano-2-(hydroxyimino)acetate] is an exceptional reagent with which to suppress rPalabras claves:amide bonds, coupling reagent, Peptides, Racemization, solid-phase synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Manne S.R.Fuentes:scopusImmobilized coupling reagents: Synthesis of amides/peptides
ReviewAbstract: The primary idea of using immobilized reagents in organic synthetic chemistry is to simplify the dowPalabras claves:combinatorial chemistry, coupling additive, high-throughput organic synthesis, solid-phase synthesis, stand-alone coupling reagentAutores:Alberício F., B. G. De la Torre, Cherkupally P., Govender T., Kruger H.G., Ramesh S.Fuentes:scopusSolid-phase N-glycopeptide synthesis using allyl side-chain protected Fmoc-amino acids
ArticleAbstract: A method for the preparation of glycopeptides using a three-dimensional orthogonal solid-phase stratPalabras claves:allyl esters, glycopeptides, Orthogonal protection, solid-phase synthesisAutores:Alberício F., B. G. De la Torre, Eritja R., Kates S.Fuentes:scopus