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A network-based approach to identify substrate classes of bacterial glycosyltransferases
ArticleAbstract: Background: Bacterial interactions with the environment- and/or host largely depend on the bacterialPalabras claves:Bacterial glycosylation, Campylobacter jejuni, Glycosyltransferases, Lactobacillus rhamnosus GG, Network-based pbkp_rediction, Sequence-based pbkp_redictionAutores:A. Sanchez Rodriguez, Aminael Sánchez-Rodríguez, Lebeer S., Marchal K., Tytgat H., Vanderleyden J., Winderickx J.Fuentes:googlerraaescopusEfficient and biologically relevant consensus strategy for Parkinson's disease gene prioritization
ArticleAbstract: Background: The systemic information enclosed in microarray data encodes relevant clues to overcomePalabras claves:Co-expression networks, Consensus strategy, early recognition, Gene prioritization, Parkinson's DiseaseAutores:A. Sanchez Rodriguez, Aminael Sánchez-Rodríguez, Borges F., Cesar Paz-y-Miño, Eduardo Tejera, Maykel Cruz-Monteagudo, Morales-Helguera A., Natalia Dias Soeiro Cordeiro M., Rebelo I., Y. Perez Castillo, Yunierkis Perez-CastilloFuentes:googlerraaescopusFrequency-based haplotype reconstruction from deep sequencing data of bacterial populations
ArticleAbstract: Clonal populations accumulate mutations over time, resulting in different haplotypes. Deep sequencinPalabras claves:Autores:A. Dubey, A. Sanchez Rodriguez, Aminael Sánchez-Rodríguez, B. Van Den Bergh, Dubey A., Fostier J., H. Steenackers, J. Fostier, J. Michiels, K. Marchal, Marchal K., Michiels J., Pulido-Tamayo S., S. Pulido-Tamayo, Steenackers H., Swings T., T. Swings, Van Den Bergh B.Fuentes:googlerraaescopusGenome-scale co-expression network comparison across Escherichia coli and Salmonella enterica serovar Typhimurium reveals significant conservation at the regulon level of local regulators despite their dissimilar lifestyles
ArticleAbstract: Availability of genome-wide gene expression datasets provides the opportunity to study gene expressiPalabras claves:Comparative genomics, comparative transcriptomics, cross, Lifestyle, regulation comparison, species expression comparisonAutores:A. Sanchez RodriguezFuentes:rraaeProbing the Hypothesis of SAR Continuity Restoration by the Removal of Activity Cliffs Generators in QSAR
ArticleAbstract: In this work we report the first attempt to study the effect of activity cliffs over the generalizatPalabras claves:Autores:A. Sanchez Rodriguez, Y. Perez CastilloFuentes:rraaeLigand-Based Virtual Screening Using Tailored Ensembles: A Prioritization Tool for Dual A2A Adenosine Receptor Antagonists / Monoamine Oxidase B Inhibitors
ArticleAbstract: Virtual Screening methodologies have emerged as efficient alternatives for the discovery of new drugPalabras claves:A2A adenosine receptors antagonist, Dual-target drugs, Ensemble modeling, MAO-B inhibitors, QSAR, Virtual ScreeningAutores:A. Sanchez Rodriguez, Y. Perez CastilloFuentes:rraae