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Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics
ArticleAbstract: We describe the synthesis and binding affinities on D2, 5-HT2A and 5-HT2C receptors of 6-aminomethylPalabras claves:antipsychotics, Butyrophenones, dopamine, Isoxazole, Pyrazole, SerotoninAutores:Barceló M., Brea J., Domínguez E., Filipe Miguel Areias, Loza M.I., Masaguer C.F., Raviña E.Fuentes:googlescopusSynthesis, 3D-QSAR, and structural modeling of benzolactam derivatives with binding affinity for the D<inf>2</inf>and D<inf>3</inf> receptors
ArticleAbstract: A series of 37 benzolactam derivatives were synthesized, and their respective affinities for the dopPalabras claves:3D-QSAR, antipsychotics, Benzolactams, D /D selectivity 2 3, Dopamine receptorsAutores:Brea J., Domínguez E., Filipe Miguel Areias, López L., Loza M.I., Masaguer C.F., Ortega R., Pastor M., Sanz F., Selent J.Fuentes:scopus