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Drug Metabolism and Personalized Therapy(1)
Frontiers in Pharmacology(1)
Pharmacogenomics Journal(1)
Pharmacogenomics in Latin America: Challenges and Opportunities(1)
Pharmacology(1)
Association of ABCB1, ABCC5 and xanthine oxidase genetic polymorphisms with methotrexate adverse reactions in Mexican pediatric patients with ALL
ArticleAbstract: Background: Acute lymphoblastic leukemia (ALL) is one of the most frequent oncological disorders inPalabras claves:Atp-Binding Cassette Transporter Gene, drug therapy/genetics, Genetic Polymorphisms, methotrexate, pharmacovigilance, precursor cell lymphoblastic leukemia-lymphoma/, xanthine oxidase (XO)Autores:Almanza-Reyes H., Chairez-Hernández I., Fausto Zaruma-Torres, Galaviz-Hernandez C., Lares-Asseff I., Loera-Castañeda V., Reyes-Espinoza A., Sosa-Macías M.G.Fuentes:rraaescopusCYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards
ArticleAbstract: Earlier we had found that the CYP2C9*2 allelic frequency was lower in Mexican-Americans living in CaPalabras claves:CYP2C9, Hispanics, Mexican-Americans, Mexican-Mestizos, Mexican-Tepehuanos, pharmacogeneticsAutores:Adrián LLerena, Alanis-Bãuelos R.E., Dorado P., Lares-Asseff I., Licinio J., Penãs-Lledó E.M., Sosa-Macías M.G., Wong M.L.Fuentes:scopusGenetic polymorphisms associated to folate transport as pbkp_redictors of increased risk for acute lymphoblastic leukemia in Mexican children
ArticleAbstract: Acute lymphoblastic leukemia (ALL) is a frequent neoplasia occurring in children. The most commonlyPalabras claves:Acute lymphoblastic leukemia, Folate transporters, Genetic Polymorphisms, methotrexate, Molecular epidemiologyAutores:Fausto Zaruma-Torres, Galaviz-Hernandez C., Lares-Asseff I., Lima A., Loera-Castañeda V., María Cristina Arias-Peláez, Quiñones L.A., Reyes-Espinoza A., Reyes-López M., Sosa-Macías M.G.Fuentes:scopusInfluence of CYP2D6 deletion, multiplication, -1584C→G, 31G→A and 2988G→A gene polymorphisms on dextromethorphan metabolism among Mexican tepehuanos and mestizos
ArticleAbstract: The aim of this study was to explain the variability of CYP2D6 activity by the identification of CYPPalabras claves:allele frequency, CYP2D6 polymorphism, Dextromethorphan metabolism, Mexican TepehuanosAutores:Adrián LLerena, Alanis-Bãuelos R.E., Dorado P., Lares-Asseff I., Sosa-Macías M.G.Fuentes:scopusImpact of genetic polymorphism of metabolic pathway of methotrexate and survival rate of Mexican children will all
ArticleAbstract: Background: Acute lymphoblastic leukemia (ALL) is a major cancer disease in Mexican pediatric populaPalabras claves:Atp-Binding Cassette Transporter Gene, Fpgs, Genetic Polymorphisms, methotrexate, Precursor cell lymphoblastic leukemia-lymphoma/*drug therapy/genetics, Survival, XOAutores:Almanza-Reyes H., Fausto Zaruma-Torres, Lares-Asseff I., Loera-Castañeda V., María Cristina Arias-Peláez, Reyes-Espinoza A.Fuentes:scopusPharmacogenomic studies in Mexico, central America and Cuba in amerindians groups: Clinical applications and toxicology
Book PartAbstract: In Latin America, the first study focused on the pharmacogenetics of CYP2D6 was developed in 1986 byPalabras claves:Clinical pharmacology, Clinician toxicology, Latin America, pharmacogenetics, PharmacogenomicsAutores:Bailón-Soto C., Fausto Zaruma-Torres, Lares-Asseff I.Fuentes:scopus