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Analysis of the Saccharomyces cerevisiae exosome architecture and of the RNA binding activity of Rrp40p
ArticleAbstract: The exosome is a complex of eleven subunits in yeast, involved in RNA processing and degradation. DePalabras claves:exosome, Protein-protein interaction, RNA binding, RNaseAutores:Fernando A. Gonzales-Zubiate, Luz J.S., Oliveira C.C., Santos M., Tavares J.Fuentes:googlescopusA mutation in human VAP-B-MSP domain, present in ALS patients, affects the interaction with other cellular proteins
ArticleAbstract: Amyotrophic Lateral Sclerosis (ALS) is the most common adult-onset Motor Neuron Disease (MND), charaPalabras claves:amyotrophic lateral sclerosis, dimerization, Protein interaction, VAP-BAutores:Fernando A. Gonzales-Zubiate, Luz J.S., Mitne-Neto M., Nishimura A., Oliveira C.C., Pimenta D.C., Ramos C., Zatz M.Fuentes:googlescopus