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Astemizole Synergizes Calcitriol Antiproliferative Activity by Inhibiting CYP24A1 and Upregulating VDR: A Novel Approach for Breast Cancer Therapy
ArticleAbstract: Background: Calcitriol antiproliferative effects include inhibition of the oncogenic ether-à-go-go-1Palabras claves:Autores:Avila-Chávez E., David B., Díaz L., Gamboa-Dominguez A., García-Becerra R., García-Quiroz J., Halhali A., Javier Camacho, Larrea F., Medina-Franco H., Ordaz-Rosado D., Rivas-Suárez M., Rodríguez P., Santos-Martínez N.Fuentes:scopusGenomic action of permanently charged tamoxifen derivatives via estrogen receptor-α
ArticleAbstract: Tamoxifen is a selective estrogen receptor modulator widely used in oncology and reproductive endocrPalabras claves:Breast Cancer, Estrogen receptor, Genomic action, Tamoxifen, Tamoxifen derivativesAutores:Bravo-Gómez M.E., Cooney A.J., García-Becerra R., Hernández-gallegos E., Javier Camacho, Larrea F., Morales-Ríos M.S., Ordaz-Rosado D., Pérez-Alvarez V., Rivera-Guevara C.Fuentes:scopusIn vivo dual targeting of the oncogenic ether-à-go-go-1 potassium channel by calcitriol and astemizole results in enhanced antineoplastic effects in breast tumors
ArticleAbstract: Background: The oncogenic ether-à-go-go-1 potassium channel (EAG1) activity and expression are necesPalabras claves:Breast Cancer, Eag1, Ki-67, Targeted therapy, vitamin D, Vitamin D receptorAutores:Avila-Chávez E., David B., Díaz L., Esparza-López J., Gamboa-Dominguez A., García-Becerra R., García-Quiroz J., Halhali A., Ibarra-Sánchez M., Javier Camacho, Larrea F., Ordaz-Rosado D., Santos-Martínez N., Villanueva O.Fuentes:scopus