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scopus(6)
Clinical implications of CYP2D6 genetic polymorphism during treatment with antipsychotic drugs
ReviewAbstract: CYP2D6 is described as the most relevant enzyme in the metabolism of many antipsychotic drugs. Its cPalabras claves:Antipsychotic drugs, CYP2D6, pharmacogenetics, PharmacogenomicsAutores:Adrián LLerena, Berecz R., Cáceres M.C., Dorado P., Penãs-Lledó E.M.Fuentes:scopusCYP2D6 polymorphism: Implications for antipsychotic drug response, schizophrenia and personality traits
ReviewAbstract: The CYP2D6 gene is highly polymorphic, causing absent (poor metabolizers), decreased, normal or incrPalabras claves:Adverse side effects, antipsychotics, CYP2D6, personality, pharmacogenetics, Pharmacogenomics, QTc, Schizophrenia, vulnerabilityAutores:Adrián LLerena, Dorado P., Penãs-Lledó E.M.Fuentes:scopusPharmacogenetic research activity in Central America and the Caribbean: A systematic review
ReviewAbstract: Aim: The present review was aimed at analyzing the pharmacogenetic scientific activity in Central AmPalabras claves:Biomarkers, Caribbean Region, Central America, pharmacogenetics, PharmacogenomicsAutores:Adrián LLerena, Campos M.D.L.A., Céspedes-Garro C., Duconge J., Humberto Fariñas, Montané-Jaime L.K., Naranjo M.E.G., Penãs-Lledó E.M., Ramirez R., Roblejo H., Rodrigues-Soares F., Serrano V., Villagrán C.I.Fuentes:scopusPharmacogenetics of debrisoquine and its use as a marker for CYP2D6 hydroxylation capacity
ReviewAbstract: Debrisoquine hydroxylation polymorphism is by far the most thoroughly studied genetic polymorphism oPalabras claves:CYP2D6, Cytochrome p450, debrisoquine, PharmacogenomicsAutores:Adrián LLerena, Dorado P., Penãs-Lledó E.M.Fuentes:scopusRelation between CYP2D6 genotype, personality, neurocognition and overall psychopathology in healthy volunteers
Conference ObjectAbstract: Aims: A lower serotonin/higher dopamine tone in CYP2D6 poor metabolizers (PMs) versus extensive metaPalabras claves:CANTAB®, CYP2D6, Impulsivity, KSP, personality, pharmacogenetics, Pharmacogenomics, SCL-90-R, TCI-RAutores:Adrián LLerena, Dorado P., González I., Pacheco R., Penãs-Lledó E.M.Fuentes:scopusRelation between CYP2D6 phenotype and genotype and personality in healthy volunteers
ArticleAbstract: Objectives: Our group has previously show that interindividual variability in CYP2D6 hydroxylation cPalabras claves:anxiety, CYP2D6, debrisoquine, KSP, personality, pharmacogenetics, PharmacogenomicsAutores:Adrián LLerena, Alvárez M., Dorado P., González I., Penãs-Lledó E.M., Pérez B.Fuentes:scopus