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A randomized, double blind, placebo-controlled trial on safety and efficacy of recombinant human insulin-like growth factor-I in children with growth hormone receptor deficiency
ArticleAbstract: GH insensitivity due to GH receptor deficiency is a rare autosomal recessive condition, characterizePalabras claves:Autores:Diamond F.B., Gargosky S.E., Jaime Guevara-Aguirre, Martinez L., Martinez V., Nonoshita L., Rosenbloom A.L., Rosenfeld R.G., Vasconez O.Fuentes:scopusFilter paper blood spot assay of human insulin-like growth factor I (IGF-I) and IGF-binding protein-3 and preliminary application in the evaluation of growth hormone status
ArticleAbstract: To facilitate broader applications of insulin-like growth factor I (IGF- I) and IGF-binding protein-Palabras claves:Autores:Diamandi A., Jaime Guevara-Aguirre, Khosravi M.J., Martinez V., Mistry J.Fuentes:scopusNormal intelligence with severe insulin-like growth factor I deficiency due to growth hormone receptor deficiency: A controlled study in a genetically homogeneous population
ArticleAbstract: Superior school performance was reported for 52 Ecuadorian probands with severe deficiency of insuliPalabras claves:Autores:Jaime Guevara-Aguirre, Kranzler J., Martinez V., Rosenbloom A.L.Fuentes:scopusKinetics of insulin-like growth factor (IGF) and IGF-binding protein responses to a single dose of growth hormone
ArticleAbstract: The in vivo physiological relationships among GH, the insulin-like growth factors (IGFs), and the IGPalabras claves:Autores:Durham S., Jaime Guevara-Aguirre, Lee P., Martinez V., Powell D., Vasconez O.Fuentes:scopusTwo-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: Comparison of two dosage levels and to GH-treated GH deficiency
ArticleAbstract: We have reported 1-yr results of a double blind, placebo-controlled trial of recombinant human insulPalabras claves:Autores:Allen L., Gargosky S.E., Jaime Guevara-Aguirre, Martinez V., Rosenbloom A.L., Rosenfeld R.G., Vasconez O.Fuentes:scopusRecombinant human insulin-like growth factor I has significant anabolic effects in adults with growth hormone receptor deficiency: Studies on protein, glucose, and lipid metabolism
ArticleAbstract: The physiological effects of insulin-like growth factor I (IGF-I) on intermediate metabolism of subsPalabras claves:Autores:Jaime Guevara-Aguirre, Martinez V., Mauras N., Rini A.Fuentes:scopus