Documentos de Hall S.R. | REDI

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Mostrando 4 resultados de: 4

Subtipo de publicación

Publisher

PLoS Neglected Tropical Diseases(1)

Scientific Reports(1)

Área temáticas

Microorganismos, hongos y algas(3)

Farmacología y terapéutica(2)

Fisiología y materias afines(1)

Medicina y salud(1)

Área de conocimiento

Biotecnología(2)

Inmunología(2)

Descubrimiento de fármacos(1)

Farmacología(1)

Año de Publicación

Origen

Palabras Claves

Small molecules(1)

Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms

Abstract: Snakebite is a neglected tropical disease that causes high rates of global mortality and morbidity.

Palabras claves:

antivenom, immunogen, neglected tropical diseases, polyclonal antibodies, recombinant expression, serine proteases, snake venom toxin, snakebite

Ainsworth S., Alomran N., Alsolaiss J., Blundell P., Casewell N.R., Crittenden E., Dawson C.A., Edge R.J., Hall S.R., Harrison R.A., Stefanie K. Menzies, Wilkinson M.C.

In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus

Abstract: Snakebite envenoming affects more than 250,000 people annually in sub-Saharan Africa. Envenoming by

Palabras claves:

Boomslang, drugs, Small molecules, snakebite, SVMP

Alsolaiss J., Casewell N.R., Clare R.H., Crittenden E., Edge R.J., Hall S.R., Harrison R.A., Kool J., Marriott A.E., Stefanie K. Menzies, Westhorpe A., Xie C.

Two snakebite antivenoms have potential to reduce Eswatini’s dependency upon a single, increasingly unavailable product: Results of preclinical efficacy testing

Abstract: Background Snakebite is a major public health concern in Eswatini, where treatment relies upon one a

Palabras claves:

Alsolaiss J., Casewell N.R., Crittenden E., Edge R.J., Hall S.R., Harrison R.A., Lalloo D.G., Litschka-Koen T., Murray J., Padidar S., Pons J., Shongwe N., Stefanie K. Menzies, Thomas B., Westhorpe A.

Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition

Abstract: Antivenom is currently the first-choice treatment for snakebite envenoming. However, only a low prop

Palabras claves:

Ainsworth S., Alsolaiss J., Casewell N.R., Crittenden E., Dawson C.A., Edge R.J., Hall S.R., Harrison R.A., Stefanie K. Menzies, Wilkinson M.C.