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scopus(5)
Frequency of S-mephenytoin hydroxylation deficiency in 373 spanish subjects compared to other Caucasian populations
ArticleAbstract: We have investigated the prevalence of poor metabolisers (PM) of S-mephenytoin in 373 unrelated, heaPalabras claves:caucasian, drug metabolism, Mephenytoin, pharmacogenetics, Phenotype, polymorphismAutores:Adrián LLerena, Benitez Rodriguez J., Bertilsson L., Carrillo J.A., Reviriego J., Valdivielso M.J.Fuentes:scopusDisposition of the neuroleptics perphenazine, zuclopenthixol, and haloperidol cosegregates with polymorphic debrisoquine hydroxylation.
ReviewAbstract:Palabras claves:Autores:Adrián LLerena, Bertilsson L., Dahl M.L., Ekqvist B.Fuentes:scopusRelationship between personality and debrisoquine hydroxylation capacity: Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6
ArticleAbstract: We administered the Karolinska Scales of Personality to 225 healthy subjects in Spain selected fromPalabras claves:debrisoquine, personality, pharmacogeneticsAutores:Adrián LLerena, Benitez Rodriguez J., Bertilsson L., Cobaleda J., Edman G., Schalling D.Fuentes:scopusReproducibility over Time of Mephenytoin and Debrisoquine Hydroxylation Phenotypes
ArticleAbstract: Mephenytoin and debrisoquine hydroxylation phenotypes were determined twice in 15 Spanish healthy voPalabras claves:Autores:Adrián LLerena, Benitez Rodriguez J., Bertilsson L., Valdivielso M.J.Fuentes:scopusThe psychostimulant khat (Catha edulis) inhibits CYP2D6 enzyme activity in humans
ArticleAbstract: The use of khat (Catha edulis) while on medication may alter treatment outcome. In particular, the iPalabras claves:cathine, cathinone, CYP2D6, dextromethorphan, drug interaction, khatAutores:Adrián LLerena, Aklillu E., Beck O., Bedada W., Bertilsson L., de Andrés F., Engidawork E., Pohanka A.Fuentes:scopus