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Insights from zebrafish and mouse models on the activity and safety of ar-turmerone as a potential drug candidate for the treatment of epilepsy
ArticleAbstract: In a previous study, we uncovered the anticonvulsant properties of turmeric oil and its sesquiterpenPalabras claves:Autores:Adriana Orellana-Paucar, Afrikanova T., Aibuldinov Y.K., De Witte P.A.M., Dehaen W., Esguerra C.V., Thomas J.Fuentes:googlescopusMethylated flavonoids as anti-seizure agents: Naringenin 4′,7-dimethyl ether attenuates epileptic seizures in zebrafish and mouse models
ArticleAbstract: Epilepsy is a neurological disease that affects more than 70 million people worldwide and is charactPalabras claves:Drug Discovery, Epilepsy, Methylated flavonoids, mouse, Naringenin, zebrafishAutores:Adriana Orellana-Paucar, Copmans D., De Borggraeve W., De Witte P.A.M., Dehaen W., Exarchou V., Foubert K., Kim Y., Ny A., Pieters L., Siekierska A., Steurs G., Zhang Y.Fuentes:googlescopusTanshinone IIA exhibits anticonvulsant activity in zebrafish and mouse seizure models
ArticleAbstract: Danshen or Chinese red sage (Salvia miltiorrhiza, Bunge) is used by traditional Chinese medicine (TCPalabras claves:mouse seizure models, pentylenetetrazol, Salvia miltiorrhiza, Tanshinone IIA, zebrafish PTZ modelAutores:Adriana Orellana-Paucar, Buenafe O.E., Crawford A.D., De Borggraeve W., De Witte P.A.M., Esguerra C.V., Huang H., Luyten W., Maes J., Ying X.Fuentes:googlescopus