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Combined effects of PI3K and SRC kinase inhibitors with imatinib on intracellular calcium levels, autophagy, and apoptosis in CML-PBL cells
ArticleAbstract: Imatinib induces a complete cytogenetic regression in a large percentage of patients affected by chrPalabras claves:apoptosis, Autophagy, Chronic myeloid leukemia, Imatinib mesylate, PI3K inhibitor, Src kinase inhibitorAutores:Boffo S., Caparrotti G., Ciarcia R., D'Angelo D., Damiano S., Fátima Morales, Florio S., Giordano A., Montagnaro S., Pagnini U., Rizzolio F., Ruocco A.Fuentes:scopusCDK9: A key player in cancer and other diseases
ArticleAbstract: Cyclin-Dependent Kinase 9 (CDK9) is part of a functional diverse group of enzymes responsible for cePalabras claves:cancer pathway, CDK9, cyclin, drug targeting, Kinase, transcription regulation, viral replicationAutores:Boffo S., Fátima Morales, Giordano A., Lia Carolina FrancoFuentes:scopusOverview of CDK9 as a target in cancer research
ReviewAbstract: CDK9 is a protein in constant development in cancer therapy. Herein we present an overview of the enPalabras claves:ANTICANCER, antitumor, CDK9, cyclin, Drug development, Kinase, molecular modelingAutores:Fátima Morales, Giordano A.Fuentes:scopus