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High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents
ArticleAbstract: Global obesity is a pandemic status, estimated to affect over 2 billion people, that has resulted inPalabras claves:Alzheimer disease, APPswe/PS1dE9, hippocampus, insulin receptor, Mitochondria, TauAutores:Antoni Camins, Artiach G., Barroso E., Carro E., Casadesús G., Ferrer I., Folch J., Pallás M., Pedros I., Petrov D., Sureda F.X., Vázquez-Carrera M., Zárate C.B.Fuentes:scopusTau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice
ArticleAbstract: The role of peroxisome proliferator activator receptor (PPAR)β/δ in the pathogenesis of Alzheimer'sPalabras claves:BACE1, Cortex, ERK1/2, PPARβ/δ, RAGE, TauAutores:Alberch J., Anglada-Huguet M., Antoni Camins, Barroso E., Del Valle J., Gutiérrez P., Michalik L., Pallás M., Palomer X., Porquet D., Rodriguez-Rodriguez R., Salvadó L., Vázquez-Carrera M., Vieira Santos A.M., Wahli W.Fuentes:scopus