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Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-γ production through the HIF-1α transcription factor
ArticleAbstract: Low oxygen tension areas are found in inflamed or diseased tissues where hypoxic cells induce survivPalabras claves:Autores:Acosta-Iborra B., Aragonés J., Calzada M.J., Elorza A., Manuel Ortiz de Landázuri, Martín-Cofreces N.B., Martin-Puig S., Miro M., Olazabal I.M., Sánchez‐Madrid F.Fuentes:scopusTargeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: The METOXIA consortium
ReviewAbstract: The hypoxic areas of solid cancers represent a negative prognostic factor irrespective of which treaPalabras claves:Bioreductive compounds, cancer-treatment resistance, carbonic anhydrase inhibitors, dual-activity compounds, non-invasive oxygen detection, targets for new treatmentAutores:Ahmed A., Alsner J., Ashcroft M., Buffa F.M., Busk M., Calzada M.J., Cao Y., Chiche J., Cojocari D., Dubois L., Ebbesen P., Flamm H., Flatmark K., Gieling R.G., Görlach A., Haider S., Harris A.L., Jobst G., Kieninger J., Koritzinsky M., Kunkler I.H., Lambin P., Langdon S.P., Lyng H., Manuel Ortiz de Landázuri, Marchiq I., Mazure N., Meehan J., Moser I., Mujcic H., Overgaard J., Parks S., Pastorekova S., Peso L.D., Pettersen E.O., Pouyssegur J., Ree A.H., Rouschop K.M., Scozzafava A., Singleton D.C., Supuran C.T., Toustrup K., Urban G., Ward C., Weltin A., Williams K.J., Wouters B.G.Fuentes:scopus