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scopus(5)
Analysis of HIF-prolyl hydroxylases binding to substrates
ArticleAbstract: Hypoxia inducible transcription factors (HIF) are mainly regulated by a group of proline hydroxylasePalabras claves:EGLN, HIF, Hypoxia, PhD, Proline-hydroxylation, VHLAutores:Cuevas Y., Manuel Ortiz de Landázuri, Peso L.D., Vara-Vega A., Vitón M.Fuentes:scopusA yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery
ArticleAbstract: Background: Several human pathologies, including neoplasia and ischemic cardiovascular diseases, couPalabras claves:Autores:Alcaide-German M.L., Garcia-Fernandez L.F., Manuel Ortiz de Landázuri, Peso L.D., Vara-Vega A.Fuentes:scopusAcute Vhl gene inactivation induces cardiac HIF-Dependent erythropoietin gene expression
ArticleAbstract: Von Hippel Lindau (Vhl) gene inactivation results in embryonic lethality. The consequences of its inPalabras claves:Autores:Albacete-Albacete L., Aragonés J., Balsa E., Elorza A., Fernández-Criado C., Fuertes E., Manuel Ortiz de Landázuri, Miró-Murillo M., Ordóñez A., Soro-Arnáiz I., Vara-Vega A., Vazquez S.N.Fuentes:scopusHIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5
ArticleAbstract: The mammalian target of rapamycin (mTOR) pathway, which is essential for cell proliferation, is reprPalabras claves:Autores:Acosta-Iborra B., Albacete-Albacete L., Aragonés J., de Cárcer G., Elorza A., Giménez-Bachs J.M., Malumbres M., Manuel Ortiz de Landázuri, Marsboom G., Martín del Río R., Meléndez-Rodríguez F., Ordóñez A., Rodríguez-Vaello V., Salinas A., Sánchez-Prieto R., Sánchez‐Madrid F., Serrano-Oviedo L., Soro-Arnáiz I., Vara-Vega A.Fuentes:scopusIdentification of a region on hypoxia-inducible-factor prolyl 4-hydroxylases that determines their specificity for the oxygen degradation domains
ArticleAbstract: HIFs [hypoxia-inducible (transcription) factors] are essential for the induction of an adaptive genePalabras claves:EGL nine homologue (EGLN), Hypoxia, Hypoxia-inducible factor (HIF), Oxygen-degradation domain (ODD), Proline hydroxylase domain (PHD), Von Hippel-Lindau protein (VHL protein)Autores:Manuel Ortiz de Landázuri, Peso L.D., Vara-Vega A., Villar D.Fuentes:scopus