Mostrando 5 resultados de: 5
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Farmacología y terapéutica(4)
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scopus(5)
A novel synthetic peptide inspired on Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusLessons from a Single Amino Acid Substitution: Anticancer and Antibacterial Properties of Two Phospholipase A<inf>2</inf>-Derived Peptides
ArticleAbstract: The membrane-active nature of phospholipase A2-derived peptides makes them potential candidates forPalabras claves:Agkistrodon, leucine, Membrane, Phenylalanine, Venom peptidesAutores:Alves C., Bruno Mendes, Fernandes P.A., Franchi G.C., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusReaction Mechanism of the PET Degrading Enzyme PETase Studied with DFT/MM Molecular Dynamics Simulations
ArticleAbstract: Polyethylene terephthalate (PET) has been widely used to make disposable bottles, among others, leadPalabras claves:biodegradation, biorecycling, density functional theory, plastic accumulation, QM/MM, umbrella samplingAutores:Carola Jerves, Fernandes P.A., Neves R.P.P., Ramos M.J., Saulo L. SilvaFuentes:scopusStructural, enzymatic and pharmacological profiles of AplTX-II - A basic sPLA<inf>2</inf> (D49) isolated from the Agkistrodon piscivorus leucostoma snake venom
ArticleAbstract: A basic sPLA2 (D49) from the venom of snake Agkistrodon piscivorus leucostoma (AplTX-II) was isolatePalabras claves:Agkistrodon piscivorus leuscostoma, Basic sPLA D49 2, molecular modeling, NOBA (4-nitro-3-octanoyloxy benzoic acid)Autores:Fernandes P.A., José Rafael de Almeida, Marangoni S., Ramos M.J., Resende L.M., Saulo L. Silva, Soares A.M., Tatiana A. Guaraca-Medina, Viegas M.F.Fuentes:scopusThe chemistry of snake venom and its medicinal potential
ReviewAbstract: The fascination and fear of snakes dates back to time immemorial, with the first scientific treatisePalabras claves:Autores:Fernandes P.A., Oliveira A.L., Ramos M.J., Saulo L. Silva, Soares A.M., Viegas M.F.Fuentes:scopus