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Comparative analysis of the effects of resveratrol in two apoptotic models: Inhibition of complex I and potassium deprivation in cerebellar neurons
ArticleAbstract: The mechanism involved in neuronal apoptosis is largely unknown. Studies performed on neuronal cellPalabras claves:Cerebellar granule cells, MPP+, Resveratrol, Serum and potassium withdrawal, Sirt1, sirtinolAutores:Alvira D., Antoni Camins, Canudas A.M., Folch J., Pallás M., Verdaguer E., Yeste-Velasco M.Fuentes:scopusDNA low-density array analysis of colchicine neurotoxicity in rat cerebellar granular neurons
ArticleAbstract: Cytoskeletal alteration is a key factor in neurodegenerative processes like Alzheimer's or ParkinsonPalabras claves:Acute toxicity, apoptosis, caspase, cell cycle, Cerebellar granule neurons, colchicine, Oxidative StressAutores:Alvira D., Antoni Camins, Folch J., Forsby A., Pallás M., Rimbau V., Sureda F.X., Yeste-Velasco M.Fuentes:scopusActivation of Akt by lithium: Pro-survival pathways in aging
ArticleAbstract: The effects of lithium on senescence were investigated using the senescence-accelerated mouse pronePalabras claves:aging, Lithium chloride, Neurodegeneration, neuroprotection, SAMP8Autores:Antoni Camins, Casadesús G., Chou S.P., Pallás M., Smith M.A., Tajes M., Yeste-Velasco M., Zhu X.Fuentes:scopusGSK-3β inhibition and prevention of mitochondrial apoptosis inducing factor release are not involved in the antioxidant properties of SB-415286
ArticleAbstract: The antioxidant effects of lithium and SB-415286, two glycogen synthase kinase-3β (GSK-3β) inhibitorPalabras claves:AIF, apoptosis, GSK-3β, Lithium, Oxidative Stress, SB-415286Autores:Antoni Camins, Folch J., Jiménez A., Pallás M., Rimbau V., Yeste-Velasco M.Fuentes:scopusGlycogen synthase kinase-3 is involved in the regulation of the cell cycle in cerebellar granule cells
ArticleAbstract: Recent studies have demonstrated that neuronal reentry in the cell cycle and specifically the expresPalabras claves:apoptosis, cell cycle, Cerebellar granule cells, GSK3β, Lithium, SB415286, Serum and potassium withdrawalAutores:Abad M.A., Antoni Camins, Enguita M., Folch J., Pallás M., Trullàs R., Yeste-Velasco M.Fuentes:scopusEvaluation of pathways involved in pentachlorophenol-induced apoptosis in rat neurons
ArticleAbstract: Pentachlorophenol (PCP) (C6HCl5O) is a synthetic toxic organochloride fungicide for humans which exhPalabras claves:Acute toxicity, apoptosis, caspase, cell cycle, Cerebellar granule neurons, Oxidative Stress, PentachlorophenolAutores:Alvira D., Antoni Camins, Bordas M., de la Torre A.V., Folch J., López-Querol M., Pallás M., Rimbau V., Sureda F.X., Yeste-Velasco M.Fuentes:scopusNeuroprotection by c-Jun NH<inf>2</inf>-terminal kinase inhibitor SP600125 against potassium deprivation-induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry
ArticleAbstract: Increasing evidence implicates the c-Jun NH2-terminal kinase (JNK) pathway in the regulation of apopPalabras claves:Akt, c-Jun NH2-terminal kinase, cell cycle, Cerebellar granule cells, SP600125Autores:Antoni Camins, Casadesús G., Folch J., Pallás M., Smith M.A., Yeste-Velasco M.Fuentes:scopusNeuroprotective effects of SB-415286 on hydrogen peroxide-induced cell death in B65 rat neuroblastoma cells and neurons
ArticleAbstract: Glycogen synthase kinase-3 (GSK-3) is involved in the pathogenesis of several neurodegenerative disePalabras claves:B65 Neuroblastoma cells, Cerebellar granule cells, H O 2 2, Lithium, Oxidative Stress, SB-415286Autores:Antoni Camins, Casadesús G., Folch J., Pallás M., Pizarro J.G., Rimbau V., Smith M.A., Yeste-Velasco M.Fuentes:scopusNeuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the ATM/p53/E2F-1 path in cerebellar granule neurons
ArticleAbstract: The aim of the present study was to evaluate the neuroprotective effects of caffeine, an inhibitor oPalabras claves:Ataxia telangiectasia mutated, caffeine, Cerebellar granule cells, Complex I inhibition, E2F-1, MPP +Autores:Alvira D., Antoni Camins, Casadesús G., Folch J., Pallás M., Smith M.A., Yeste-Velasco M.Fuentes:scopusModulation of SIRT1 expression in different neurodegenerative models and human pathologies
ArticleAbstract: We examined the expression of SIRT1 in several experimental paradigms of human pathologies. We usedPalabras claves:3-nitropropionic acid, BRAIN, cell cycle, kainate, MPP+, rotenoneAutores:Alvira D., Antoni Camins, Canudas A.M., Crespo-Biel N., Ferrer I., Folch J., Gutiérrez-Cuesta J., Pallás M., Pizarro J.G., Sureda F.X., Tajes M., Yeste-Velasco M.Fuentes:scopus