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Activation of Akt by lithium: Pro-survival pathways in aging
ArticleAbstract: The effects of lithium on senescence were investigated using the senescence-accelerated mouse pronePalabras claves:aging, Lithium chloride, Neurodegeneration, neuroprotection, SAMP8Autores:Antoni Camins, Casadesús G., Chou S.P., Pallás M., Smith M.A., Tajes M., Yeste-Velasco M., Zhu X.Fuentes:scopusGlycogen synthase kinase-3 is involved in the regulation of the cell cycle in cerebellar granule cells
ArticleAbstract: Recent studies have demonstrated that neuronal reentry in the cell cycle and specifically the expresPalabras claves:apoptosis, cell cycle, Cerebellar granule cells, GSK3β, Lithium, SB415286, Serum and potassium withdrawalAutores:Abad M.A., Antoni Camins, Enguita M., Folch J., Pallás M., Trullàs R., Yeste-Velasco M.Fuentes:scopusNeuroprotection by c-Jun NH<inf>2</inf>-terminal kinase inhibitor SP600125 against potassium deprivation-induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry
ArticleAbstract: Increasing evidence implicates the c-Jun NH2-terminal kinase (JNK) pathway in the regulation of apopPalabras claves:Akt, c-Jun NH2-terminal kinase, cell cycle, Cerebellar granule cells, SP600125Autores:Antoni Camins, Casadesús G., Folch J., Pallás M., Smith M.A., Yeste-Velasco M.Fuentes:scopusNeuroprotective effects of SB-415286 on hydrogen peroxide-induced cell death in B65 rat neuroblastoma cells and neurons
ArticleAbstract: Glycogen synthase kinase-3 (GSK-3) is involved in the pathogenesis of several neurodegenerative disePalabras claves:B65 Neuroblastoma cells, Cerebellar granule cells, H O 2 2, Lithium, Oxidative Stress, SB-415286Autores:Antoni Camins, Casadesús G., Folch J., Pallás M., Pizarro J.G., Rimbau V., Smith M.A., Yeste-Velasco M.Fuentes:scopusNeuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the ATM/p53/E2F-1 path in cerebellar granule neurons
ArticleAbstract: The aim of the present study was to evaluate the neuroprotective effects of caffeine, an inhibitor oPalabras claves:Ataxia telangiectasia mutated, caffeine, Cerebellar granule cells, Complex I inhibition, E2F-1, MPP +Autores:Alvira D., Antoni Camins, Casadesús G., Folch J., Pallás M., Smith M.A., Yeste-Velasco M.Fuentes:scopusProsurvival role of JAK/STAT and Akt signaling pathways in MPP <sup>+</sup>-induced apoptosis in neurons
ArticleAbstract: In the present study the role of JAK/STAT and Akt in apoptosis was evaluated in cerebellar granule cPalabras claves:Akt, apoptosis, MPP +, STAT3, Cerebellar granule cellsAutores:Alvira D., Antoni Camins, de la Torre A.V., Folch J., Junyent F., Pallás M., Sureda F.X., Verdaguer E., Yeste-Velasco M., Zárate C.B.Fuentes:scopusThe antiproliferative activity of melatonin in B65 rat dopaminergic neuroblastoma cells is related to the downregulation of cell cycle-related genes
ArticleAbstract: A potential application of melatonin is its ability to rescue many cell types from cell death, becauPalabras claves:apoptosis, B65, cell cycle, melatonin, NeuroblastomaAutores:Antoni Camins, Esparza J.L., Folch J., Pallás M., Pizarro J.G., Verdaguer E., Yeste-Velasco M.Fuentes:scopusThe p38<sup>MAPK</sup> signaling pathway regulates neuronal apoptosis through the phosphorylation of the retinoblastoma protein
ArticleAbstract: We investigated the role of SB202190, a selective p38 mitogen-activated protein kinase (MAPK) inhibiPalabras claves:cell cycle, Cerebellar granule cells, E2F-1, S/K deprivationAutores:Antoni Camins, Folch J., Pallás M., Yeste-Velasco M.Fuentes:scopus