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Low-Versus Standard-Dose Alteplase in Patients on Prior Antiplatelet Therapy the ENCHANTED Trial (Enhanced Control of Hypertension and Thrombolysis Stroke Study)
Conference ObjectAbstract: Background and Purpose'Many patients receiving thrombolysis for acute ischemic stroke are on prior aPalabras claves:aspirin, Brain Infarction, Hypertension, intracranial hemorrhages, Tissue plasminogen activatorAutores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Demchuk A.M., Donnan G.A., Kim J.S., Lavados P.M., Lee T.H., Lindley R.I., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sato S., Sharma V.K., Wang J.G., Wang X., Woodward M.Fuentes:scopusLow-dose vs standard-dose alteplase for patients with acute ischemic stroke: Secondary analysis of the ENCHANTED randomized clinical trial
ArticleAbstract: IMPORTANCE: A lower dose of intravenous alteplase appears to be a safer treatment option than the stPalabras claves:Autores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Demchuk A.M., Donnan G.A., Kim J.S., Lavados P.M., Lee T.H., Li Q., Lindley R.I., Martins S.O., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sharma V.K., Thang N.H., Wang J.G., Wang X., Woodward M.Fuentes:scopusIntensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial
ArticleAbstract: Background: Systolic blood pressure of more than 185 mm Hg is a contraindication to thrombolytic trePalabras claves:Autores:Arima H., Armenis M., Bai X., Baig M.A., Bath P.M.W., Benito D., Billot L., Blacklock N., Bousser M.G., Broderick J.P., Cao Y., Carcel C., Chalmers J., Chen G., Chen R., Chen X., Cong Y., Coutts S., Cui B., Delcourt C., Demchuk A.M., Deng H., Donnan G.A., Donnelly P., Durham A.C., Fuentes-Patarroyo S.X., Glass P., Gordon P., Guo Y., Hankey G.J., Haunton V., He R., Hirakawa Y., Huang Y., Ivanova E., Jenson K., Jia H., Kim J.S., Knight E., Kong L., Kumar N.N., Kunchok A., Lavados P.M., Levi C., Li Q., Lim J.Y., Lindley R.I., Liu L., Lv J., Malavera A., Manning L., Martins S.O., Minhas J.S., Mistri A., Monaghan H., Moullaali T.J., Naidu B., Octavio Marques Pontes-Neto, Odgers E., Olavarria V.V., Parsons M.W., Ricci S., Richtering S., Robinson T.G., S Anderson C., Sandercock P., Sanders E., Sato S., Scaria A., Sharma V.K., Silva-Sieger F.A., Simes R.J., Small S., Smith P., Song L., Stapf C., Tay N., Thang N.H., Thembani E., Tucker S., Vaghasiya R., Wang J.G., Wang X., Wardlaw J.M., Winters S., Wong K.S.L., Woodward M., Wu G., Xi Z., Yang J., Yoshimura S., You S., Zhang S., Zhao H., Zhu P.Fuentes:scopusLipid-lowering pretreatment and outcome following intravenous thrombolysis for acute ischaemic stroke: a post hoc analysis of the enhanced control of hypertension and thrombolysis stroke study trial
ArticleAbstract: Background: Debate exists as to whether statin pretreatment confers an increased risk of 90-day mortPalabras claves:Acute stroke outcome, Intracranial haemorrhage, Lipid-lowering therapy, OR, RISK FACTORS, statins, strokeAutores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Donnan G.A., Kim J.S., Lavados P.M., Lee T.H., Martins S.O., Minhas J.S., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Ricci S., Robinson T.G., S Anderson C., Sato S., Sharma V.K., Thang N.H., Wang J.G., Wang X., Woodward M.Fuentes:scopus