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Nasal administration of the neuroprotective candidate NeuroEPO to healthy volunteers: A randomized, parallel, open-label safety study
ArticleAbstract: Background: Delivery of therapeutic agents as erythropoietin (EPO) into Central Nervous System throuPalabras claves:Healthy volunteers, Hematopoietic activity, neurodegenerative diseases, NeuroEPO, Non-hematopoietic recombinant erythropoietin, safety, strokeAutores:Alfonso-Muñoz E., Amaro-González D., Carmen Elena Viada, Díaz-Machado A., Festary-Casanovas T., García-García I., González-Delgado C.A., Jiménez-Rodríguez D., Pérez-Rodríguez S., Piedra-Sierra P., Pomares-Iturralde Y., Santos-Morales O.Fuentes:scopusPharmacokinetic and pharmacodynamic characterization of a novel formulation containing co-formulated interferons alpha-2b and gamma in healthy male volunteers
ArticleAbstract: Background: More potent antitumor activity is desired in Interferon (IFN)-treated cancer patients. TPalabras claves:2'-5' oligoadenylate synthetase, Beta2-microglobulin, interferons, Neopterin, pharmacodynamics, pharmacokineticsAutores:Bello-Rivero I., Campos-Mojena R., Cruz-Ramírez A., Díaz-Machado A., García-Vega Y., González-Delgado C.A., Hernández-González I., I. Howland-Álvarez, López-Saura P.A., Martín-Trujillo A., Pérez-Rodríguez S., Santana-Milián H., Tuero-Iglesias Á.D., Valenzuela-Silva C.M.Fuentes:scopus