Mostrando 10 resultados de: 20
Filtros aplicados
Publisher
Arzneimittel-Forschung/Drug Research(2)
Molecules(2)
Tetrahedron Letters(2)
Acta Crystallographica Section E: Structure Reports Online(1)
Arkivoc(1)
Área temáticas
Química orgánica(12)
Química y ciencias afines(5)
Bioquímica(4)
Química física(3)
Microorganismos, hongos y algas(2)
Chemical Conjugation in Drug Delivery Systems
ReviewAbstract: Cancer is one of the diseases with the highest mortality rate. Treatments to mitigate cancer are usuPalabras claves:Biomolecules, Carriers, covalent bioconjugation, Drug delivery systems, linkersAutores:Alberício F., Alexis Eras, Danna Castillo, Hortensia Rodriguez Cabrera, Santiago Nelson Vispo, Suárez Navarro M.Fuentes:scopusA convenientmicrowave-enhanced solid-phase synthesis of short chain N-methyl-rich peptides
ArticleAbstract: Structural modification of the peptide backbone via N-methylation is a powerful tool to modulate thePalabras claves:Fmoc-N-methyl amino acids, MICROWAVE, Solid-phase peptide synthesisAutores:Alberício F., Hortensia Rodriguez Cabrera, Suárez Navarro M.Fuentes:scopusDevelopment of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors
ArticleAbstract: The implementation of a novel sequential computational approach that can be used effectively for virPalabras claves:Autores:Andrew L.C., Burgos A., Fairlamb A.H., Hortensia Rodriguez Cabrera, Jones D.C., Perez-Pineiro R., Suárez Navarro M., Wishart D.S.Fuentes:googlescopusAlkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents
ArticleAbstract: The effect of several alkyl-linked bis tetrahydro-(2H)-1,3,5-thiadiazine-2- thione (bis-THTT) on LeiPalabras claves:Alkyl-linked bis-THTT anti-protozoal activityAutores:Alvarez A., Atherton R., Coro J., Hortensia Rodriguez Cabrera, Little S., Perez-Pineiro R., Suárez Navarro M., Wharton H., Yardley V.Fuentes:googlescopusAn Androsterone-H<inf>2</inf>@C<inf>60</inf> hybrid: Synthesis, Properties and Molecular Docking Simulations with SARS-Cov-2
ArticleAbstract: We report the synthesis and characterization of a fullerene-steroid hybrid that contains H2@C60 andPalabras claves:cyclopropanation, Fullerenes, Molecular docking, SARS-COV-2, Steroid hybridsAutores:Alberício F., Almagro L., Herranz M.Á., Hortensia Rodriguez Cabrera, Lemos R., Makowski K., Maroto E., Martín N., Molero D., Murata Y., Ortiz O., Suárez Navarro M.Fuentes:scopusEco-friendly methodology to prepare N-heterocycles related to dihydropyridines: Microwave-assisted synthesis of alkyl 4-arylsubstituted-6- chloro-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate and 4-arylsubstituted-4,7-dihydrofuro[3,4-b]pyridine-2,5(1H,3H)-dione
ArticleAbstract: Here we describe the efficient synthesis of alkyl 4-arylsubstituted-6- chloro-5- formyl-2-methyl-1,4Palabras claves:Dihydropyridines, Green Chemistry, MICROWAVEAutores:Alberício F., Hortensia Rodriguez Cabrera, Martín N., Martín O., Suárez Navarro M.Fuentes:googlescopusEfficient sonochemical synthesis of alkyl 4-aryl-6-chloro-5-formyl-2- methyl-1,4-dihydropyridine-3-carboxylate derivatives
ArticleAbstract: A facile, efficient and environment-friendly protocol for the synthesis of 6-chloro-5-formyl-1,4-dihPalabras claves:1,4-Dihydropyridine derivatives, Sonochemistry, ultrasound irradiation, Vilsmeier-Haack reactionAutores:Coro J., Enrique Ruiz-Reyes, Hortensia Rodriguez Cabrera, Martín N., Martínez-Álvarez R., Niebla V., Novoa De Armas H., Rodríguez A., Suárez Navarro M.Fuentes:googlescopusMorphological characterization of fullerene-androsterone conjugates
ArticleAbstract: Here we report on the self-organization characteristics in water of two diastereomer pairs of fullerPalabras claves:Androsterone, dynamic light scattering, Fullerene, Transmission electron microscopyAutores:Alberício F., Hortensia Rodriguez Cabrera, Martín N., Ruiz A., Suárez Navarro M.Fuentes:scopusHigh-throughput preparation of alkyl 4-aryl substituted-2-methyl-6-thioxo- 1,4,5,6-tetrahydropyridine-3-carboxylates under microwave irradiation
ArticleAbstract: An efficient high-throughput synthesis of 4-aryl substituted 1,4,5,6-tetrahydro-2-methyl-6-thioxopyrPalabras claves:heterocycles, Lawesson's reagent, Microwave irradiation, Theoretical calculation, ThiopyridonesAutores:Alberício F., Coro J., Hortensia Rodriguez Cabrera, Lam A., Martín N., Rodríguez-Salarichs J., Salfrán E., Suárez Navarro M.Fuentes:googlescopusIn vitro activities of thiadiazine derivatives against Leishmania amazonensis
ArticleAbstract: Ten thiadiazine derivatives were tested in vitro for antiparasitic effects against both extracellulaPalabras claves:Antiparasitic drugs, Leishmania amazonensis, amastigotes, promastigotes, Thiadiazine derivatives, antileishmanial activity in vitro, toxicityAutores:Fonseca L., Hortensia Rodriguez Cabrera, Montalvo Álvarez A.M., Monzote L., Perez-Pineiro R., Suárez Navarro M.Fuentes:googlescopus