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An in-line enzymatic microreactor for the middle-up analysis of monoclonal antibodies by capillary electrophoresis
ArticleAbstract: Monoclonal antibodies (mAbs) are undergoing rapid growth in the pharmaceutical industry due to theirPalabras claves:Autores:Bich C., Bonnet P.A., Christian Larroque, Dadouch M., Ladner Y., Larroque M., Morel J., Perrin C.Fuentes:scopusFANCD2 Binds MCM Proteins and Controls Replisome Function upon Activation of S Phase Checkpoint Signaling
ArticleAbstract: Proteins disabled in Fanconi anemia (FA) are necessary for the maintenance of genome stability durinPalabras claves:Autores:Bec N., Christian Larroque, Constantinou A., Décaillet C., Gari K., Larroque M., Lossaint G., Ribeyre C.Fuentes:scopusRecruitment of ubiquitin-activating enzyme UBA1 to DNA by poly(ADP-ribose) promotes ATR signalling
ArticleAbstract: The DNA damage response (DDR) ensures cellular adaptation to genotoxic insults. In the crowded envirPalabras claves:Autores:Basbous J., Christian Larroque, Constantinou A., Kontopoulos D.G., Kossida S., Kumbhar R., Larroque M., Ribeyre C., Vidal-Eychenié S.Fuentes:scopusThe organizer of chromatin topology RIF1 ensures cellular resilience to DNA replication stress
ArticleAbstract: Eukaryotic genomes are duplicated from thousands of replication origins that fire sequentially formiPalabras claves:Autores:Christian Larroque, Larroque M., Lebdy R., Merhi R.A., Patouillard J., Ribeyre C., Urbach S.Fuentes:scopus