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B epitope multiplicity and B/T epitope orientation influence immunogenicity of foot-and-mouth disease peptide vaccines
ArticleAbstract: Synthetic peptides incorporating protective B- and T-cell epitopes are candidates for new safer footPalabras claves:Autores:Andreu D., B. G. De la Torre, Bárcena J., Blanco E., Cubillos C., Moreno N., Sobrino F.Fuentes:scopusA DNA vaccine expressing the E2 protein of classical swine fever virus elicits T cell responses that can prime for rapid antibody production and confer total protection upon viral challenge
ArticleAbstract: Immunization of domestic pigs with a DNA vaccine expressing the complete E2 protein of classical swiPalabras claves:CSFV, DNA immunization, Marker vaccine, T cell responseAutores:Blanco I., Frias M.T., Ganges L., Maritza Barrera, Núñez J.I., Rodríguez F., Sobrino F.Fuentes:scopusA T-cell epitope on NS3 non-structural protein enhances the B and T cell responses elicited by dendrimeric constructions against CSFV in domestic pigs
ArticleAbstract: It has been recently reported by our group that dendrimeric constructs combining B- and T-cell epitoPalabras claves:Cellular and humoural immune response, Classical swine fever virus, Dendrimeric peptide vaccine, Epitopes, Marker (DIVA) vaccineAutores:Andreu D., B. G. De la Torre, Domingo M., Fraile L., Ganges L., Monsó M., Muñoz M., Nofrarías M., Pérez L.J., Riquelme C., Rosell R., Sobrino F., Tarradas J.Fuentes:scopusDendrimeric peptides can confer protection against foot-and-mouth disease virus in cattle
ArticleAbstract: Foot-and-mouth disease virus (FMDV) causes a highly contagious disease in cloven-hoofed animals. A sPalabras claves:Autores:Andreu D., B. G. De la Torre, Blanco E., Digiacomo S., Gammella M., Langellotti C., Montoya M., Quattrocchi V., Sobrino F., Soria I., Zamorano P.Fuentes:scopusFull protection of swine against foot-and-mouth disease by a bivalent B-cell epitope dendrimer peptide
ArticleAbstract: Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed animals. WePalabras claves:foot-and-mouth disease virus, Peptide dendrimers, PROTECTION, vaccinesAutores:Andreu D., B. G. De la Torre, Blanco E., Defaus S., Dekker A., Guerra B., Sobrino F.Fuentes:scopusEnhanced mucosal immunoglobulin A response and solid protection against foot-and-mouth disease virus challenge induced by a novel dendrimeric peptide
ArticleAbstract: The successful use of a dendrimeric peptide to protect pigs against challenge with foot-and-mouth diPalabras claves:Autores:Andreu D., B. G. De la Torre, Bárcena J., Blanco E., Borrás E., Clementi G., Cubillos C., Jakab A., Sobrino F.Fuentes:scopusMutations that hamper dimerization of foot-and-mouth disease virus 3A protein are detrimental for infectivity
ArticleAbstract: Foot-and-mouth disease virus (FMDV) nonstructural protein 3A plays important roles in virus replicatPalabras claves:Autores:Andreu D., B. G. De la Torre, Gómez-Puertas P., González-Magaldi M., Kremer L., López-Viñas E., Postigo R., Rodríguez-Pulido M., Rosas M.F., Sobrino F., Vieira Y.A.Fuentes:scopusOrigin and evolution of viruses causing classical swine fever in Cuba
ArticleAbstract: We have analyzed the origin and evolution of viruses from the classical swine fever (CSF) epidemic tPalabras claves:classical swine fever, Genetic typing, Molecular epidemiology, Virus evolutionAutores:De Arce H.D., Frias M.T., Ganges L., Maritza Barrera, Naranjo D., Núñez J.I., Sobrino F.Fuentes:scopusInclusion of a specific T cell epitope increases the protection conferred against foot-and-mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site
ArticleAbstract: Background. Foot-and-mouth disease virus (FMDV) causes an economically important and highly contagioPalabras claves:FMDV, foot-and-mouth disease virus, Linear peptides, pig, Swine, VaccineAutores:Andreu D., B. G. De la Torre, Bárcena J., Blanco E., Cubillos C., Sobrino F.Fuentes:scopusImmune response and partial protection against heterologous foot-and-Mouth disease virus induced by dendrimer peptides in cattle
ArticleAbstract: Synthetic peptides mimicking protective B- and T-cell epitopes are good candidates for safer, more ePalabras claves:Autores:Andreu D., B. G. De la Torre, Blanco E., Bucafusco D., Di Giacomo S., Gnazzo V., Langellotti C., Pega J., Pérez-Filgueira M., Quattrocchi V., Romera S., Schammas J., Sobrino F., Soria I., Zamorano P.Fuentes:scopus