Mostrando 10 resultados de: 11
Filtros aplicados
Publisher
Current Drug Metabolism(2)
Bipolar Disorders(1)
Brain Research(1)
British Journal of Pharmacology(1)
Current Pharmaceutical Design(1)
Área temáticas
Enfermedades(9)
Bioquímica(3)
Farmacología y terapéutica(3)
Fisiología humana(3)
Fisiología y materias afines(2)
Origen
scopus(11)
Antiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusAntiapoptotic effects of roscovitine in cerebellar granule cells deprived of serum and potassium: A cell cycle-related mechanism
ArticleAbstract: Neuronal apoptosis may be partly due to inappropriate control of the cell cycle. We used serum depriPalabras claves:apoptosis, Caspase-3, cell cycle, cyclin, E2F-1, RoscovitineAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Verdaguer E.Fuentes:scopusCalpains as a target for therapy of neurodegenerative diseases: Putative role of lithium
ReviewAbstract: Lithium is a simple cation that has been used clinically since 1950 for the treatment of bipolar disPalabras claves:apoptosis, Calcium homeostasis, Calpain, Cell cycle control, Cytoskeleton, DNA damage, Kinases, Lithium, Neurodegeneration, neurodegenerative diseases, signal transduction, Tau kinasesAutores:Antoni Camins, Canudas A.M., Crespo-Biel N., Junyent F., Pallás M., Verdaguer E.Fuentes:scopusNeurotoxicity of amphetamine derivatives is mediated by caspase pathway activation in rat cerebellar granule cells
ArticleAbstract: The neurotoxic action of the abuse drugs methamphetamine (METH) and 3,4-methylenedioxymethamphetaminPalabras claves:apoptosis, Caspases, Cerebellar granule neurones, Cytochrome c, MDMA, MethamphetamineAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Sureda F.X., Verdaguer E.Fuentes:scopusImplication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium
ArticleAbstract: Although numerous studies have demonstrated a neuroprotective and anti-apoptotic role of lithium inPalabras claves:apoptosis, Cdk5/p25, Cerebellar granule neurons, GSK-3β, LithiumAutores:Allgaier C., Antoni Camins, Canudas A.M., Garcia De Arriba S., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusInhibition of ataxia telangiectasia-p53-E2F-1 pathway in neurons as a target for the prevention of neuronal apoptosis
ReviewAbstract: Over the last few decades, understanding of the mechanisms involved in the process of neuronal'cellPalabras claves:apoptosis, Cyclin dependent kinases, E2F-1, NeuronAutores:Antoni Camins, Canudas A.M., Folch J., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopusInhibition of multiple pathways accounts for the antiapoptotic effects of flavopiridol on potassium withdrawal-induced apoptosis in neurons
ArticleAbstract: Serum and potassium (S/K) deprivation is a well-known apoptotic model in cerebellar granule neuronsPalabras claves:apoptosis, Cdk, cell cycle, flavopiridol, GSK-3β, MEF2Autores:Alvira D., Antoni Camins, Canudas A.M., Folch J., Jiménez A., Jordá E.G., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopusLithium prevents colchicine-induced apoptosis in rat cerebellar granule neurons
ArticleAbstract: Objectives: Here we evaluated the neuroprotective effects of two well-known mood stabilizers, lithiuPalabras claves:apoptosis, colchicine, Lithium, neuroprotectionAutores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Morano A., Pallás M., Verdaguer E.Fuentes:scopusKainic acid-induced apoptosis in cerebellar granule neurons: An attempt at cell cycle re-entry
ArticleAbstract: This study was undertaken to investigate whether kainic acid (KA) may regulate the expression of sevPalabras claves:apoptosis, Cdk, cell cycle, Cyclines, E2F-1, Kainic acidAutores:Antoni Camins, Canudas A.M., Domínguez E., Escubedo E., García-Jordà E., Jiménez A., Pallás M., Pubill D., Verdaguer E.Fuentes:scopusKainic acid-induced neuronal cell death in cerebellar granule cells is not prevented by caspase inhibitors
ArticleAbstract: 1. We examined the role of non-NMDA receptors in kainic acid (KA)-induced apoptosis in cultures of rPalabras claves:Ac-DEVD-CHO, apoptosis, Calpain, Caspases, Cerebellar granule cells, colchicine, glutamate, Kainic acid, Par-4, Z-VAD.fmkAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., García-Jordà E., Jiménez A., Pallás M., Stranges A., Sureda F.X., Verdaguer E.Fuentes:scopus