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Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy
ArticleAbstract: Abiraterone blocks androgen synthesis and prolongs survival in patients with castration-resistant prPalabras claves:Autores:Abazeed M., Alyamani M., Balk S., Li J., Li Z., Richard J. Auchus, Rogacki K., Sharifi N., Taplin M., Upadhyay S.K.Fuentes:scopusSteroidogenic Metabolism of Galeterone Reveals a Diversity of Biochemical Activities
ArticleAbstract: Galeterone is a steroidal CYP17A1 inhibitor, androgen receptor (AR) antagonist, and AR degrader, undPalabras claves:3βHSD, abiraterone, Androgens, CYP17A1, galeterone, metabolism, Prostate cancer, steroidsAutores:Alyamani M., Berk M.P., Li J., Li Z., Richard J. Auchus, Sharifi N., Tang J., Upadhyay S.K.Fuentes:scopus