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Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM)
ArticleAbstract: Tau is a neuronal microtubule-associated protein found predominantly on axons. Tau phosphorylation rPalabras claves:aging, Cdk5/p25, Senescence-accelerated mice, Tau proteinAutores:Acuña-Castroviejo D., Antoni Camins, Canudas A.M., Gutiérrez-Cuesta J., Pallás M., Rodríguez M.I., Sureda F.X.Fuentes:scopusInhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease
ArticleAbstract: In this study, the effects of melatonin on MPP+-treated cerebellar granule neurons (CGNs) in culturePalabras claves:apoptosis, Calpain, caspase, CDK5, Cerebellar granule cells, MPP +Autores:Acuña-Castroviejo D., Alvira D., Antoni Camins, Folch J., Pallás M., Tajes M., Verdaguer E.Fuentes:scopus