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Applicability of ENCHANTED trial results to current acute ischemic stroke patients eligible for intravenous thrombolysis in England and Wales: Comparison with the Sentinel Stroke National Audit Programme registry
ArticleAbstract: Background: Randomized controlled trials provide high-level evidence, but the necessity to include sPalabras claves:acute ischemic stroke, Alteplase, Clinical trial, health outcomes, thrombolysisAutores:Arima H., Bath P.M.W., Bray B.D., Broderick J.P., Chalmers J., Durham A.C., Kim J.S., Lavados P.M., Lee T.H., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Paley L., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., Rudd A.G., S Anderson C., Sharma V.K., Sprigg N., Wang J.G., Wang X., Woodward M.Fuentes:scopusRationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy (ENCHANTED) trial: An international multicenter 2×2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment
ArticleAbstract: Rationale: Controversy exists over the optimal dose of intravenous (iv) recombinant tissue plasminogPalabras claves:Acute ischaemic stroke, Alteplase, Dose, Hypertension, Rt-PA, thrombolysisAutores:Arima H., Bath P.M.W., Broderick J.P., Chalmers J., Chen X., Demchuk A.M., Donnan G.A., Fuentes S., Huang Y., Kim J.S., Lavados P.M., Lee T.H., Levi C., Lindley R.I., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sharma V.K., Silva-Sieger F.A., Stapf C., Wang J.G., Woodward M.Fuentes:scopusRegional variation in acute stroke care organisation
ArticleAbstract: Background Few studies have assessed regional variation in the organisation of stroke services, partPalabras claves:acute ischemic stroke, In- and out-hospital stroke care organisation, Intracerebral Hemorrhage, stroke, Stroke care, thrombolysisAutores:Arima H., Billot L., Cui L., De Silva H.A., Hackett M.L., Lavados P.M., Lee T.H., Lim J.Y., Lin R.T., Mead G.E., Middleton S., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Peng B., Robinson T.G., S Anderson C., Song L., Venturelli P.M., Watkins C.L.Fuentes:scopus