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Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17β-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells
ArticleAbstract: Human 17β-hydroxysteroid dehydrogenase types 1 and 2 (17βHSD1 and 17βHSD2) regulate estrogen potencyPalabras claves:Autores:Akbar S., Guryev O.L., Mizrachi D., Papari-Zareei M., Rambally S., Richard J. Auchus, Sherbet D.P.Fuentes:scopusCYP17 mutation E305G causes isolated 17,20-lyase deficiency by selectively altering substrate binding
ArticleAbstract: Cytochrome P450c17 (CYP17) converts the C21 steroids pregnenolone and progesterone to the C19 androgPalabras claves:Autores:Hochberg Z., Kwist K.W., Richard J. Auchus, Sherbet D.P., Tiosano D.Fuentes:scopus