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Biochimica et Biophysica Acta - General Subjects(1)
Endocrine Research(1)
Journal of Steroid Biochemistry and Molecular Biology(1)
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Bioquímica(3)
Farmacología y terapéutica(1)
Fisiología humana(1)
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scopus(3)
Comparison of the hamster and human adrenal P450c17 (17α-hydroxylase/17,20-lyase) using site-directed mutagenesis and molecular modeling
ArticleAbstract: In order to understand the activity specificity of the hamster cytochrome P450 17α-hydroxylase/17,20Palabras claves:17,20-Lyase, 17α-hydroxylase, 3D modeling, Adrenals, CYP17, Cytochrome P450c17, HÁMSTER, Human, Mutants, Site-directed mutagenesisAutores:LeHoux J.G., Mathieu A.P., Richard J. AuchusFuentes:scopusMolecular modeling of the hamster adrenal P450C17
Conference ObjectAbstract: The cytochrome P450C17 (C17) is the steroidogenic enzyme responsible for the conversion of pregnenolPalabras claves:Autores:LeHoux J.G., Mathieu A.P., Richard J. AuchusFuentes:scopusMolecular dynamics of substrate complexes with hamster cytochrome P450c17 (CYP17): Mechanistic approach to understanding substrate binding and activities
Conference ObjectAbstract: The cytochrome P450c17 isoforms from various animal species have different substrate selectivity, esPalabras claves:17α-Hydroxylase/17,20-lyase, Computer modeling, Cytochrome P450c17 (CYP17), Hamster adrenal gland, molecular dynamics, Steroid hormoneAutores:LeHoux J.G., Mathieu A.P., Richard J. AuchusFuentes:scopus