Comparison of the hamster and human adrenal P450c17 (17α-hydroxylase/17,20-lyase) using site-directed mutagenesis and molecular modeling

Article

Abstract: In order to understand the activity specificity of the hamster cytochrome P450 17α-hydroxylase/17,20

Palabras claves:

17,20-Lyase, 17α-hydroxylase, 3D modeling, Adrenals, CYP17, Cytochrome P450c17, HÁMSTER, Human, Mutants, Site-directed mutagenesis

Autores:

LeHoux J.G., Mathieu A.P., Richard J. Auchus

Fuentes:

scopus