Isocitrate dehydrogenase 1 mutation drives leukemogenesis by PDGFRA activation due to insulator disruption in acute myeloid leukemia (AML)

Article

Abstract: Acute myeloid leukemia (AML) is characterized by complex molecular alterations and driver mutations.

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Autores:

Baldus C.D., Bastian L., Beder T., Bultmann M., Fransecky L., Hänzelmann S., Hartmann A., Hübner E., Lenk L., Lipinski S., Neumann M., Richter K., Röllig C., Schewe D.M., Schultz K., Silva P., Spielmann M., Steinhäuser S., Verónica Yumiceba, Vogiatzi F., Xia S.

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