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Comparative analysis of the effects of resveratrol in two apoptotic models: Inhibition of complex I and potassium deprivation in cerebellar neurons
ArticleAbstract: The mechanism involved in neuronal apoptosis is largely unknown. Studies performed on neuronal cellPalabras claves:Cerebellar granule cells, MPP+, Resveratrol, Serum and potassium withdrawal, Sirt1, sirtinolAutores:Alvira D., Antoni Camins, Canudas A.M., Folch J., Pallás M., Verdaguer E., Yeste-Velasco M.Fuentes:scopusDNA low-density array analysis of colchicine neurotoxicity in rat cerebellar granular neurons
ArticleAbstract: Cytoskeletal alteration is a key factor in neurodegenerative processes like Alzheimer's or ParkinsonPalabras claves:Acute toxicity, apoptosis, caspase, cell cycle, Cerebellar granule neurons, colchicine, Oxidative StressAutores:Alvira D., Antoni Camins, Folch J., Forsby A., Pallás M., Rimbau V., Sureda F.X., Yeste-Velasco M.Fuentes:scopusActivation of ataxia telangiectasia muted under experimental models and human Parkinson's disease
ArticleAbstract: In the present study we demonstrated that neurotoxin MPP +-induced DNA damage is followed by ataxiaPalabras claves:apoptosis, ATM, B65 neuroblastoma, cell cycle, MPP +, Parkinson's Disease, Retinoblastoma proteinAutores:Alvira D., Antoni Camins, de la Torre A.V., Ferrer I., Folch J., Gutiérrez-Cuesta J., Jordan J., Junyent F., Pallás M., Pizarro J.G., Sureda F.X., Verdaguer E.Fuentes:scopusActivation of the calpain/cdk5/p25 pathway in the girus cinguli in Parkinson's disease
ArticleAbstract: The mechanisms involved in neuronal loss in Parkinson's disease (PD) are not known, although recentPalabras claves:CDK5, cell cycle, E2F-1, Parkinson's DiseaseAutores:Alvira D., Antoni Camins, Ferrer I., Garcia-Castro B., Gutiérrez-Cuesta J., Pallás M.Fuentes:scopusEvaluation of acute antiapoptotic effects of Li<sup>+</sup> in neuronal cell cultures
ArticleAbstract: Li+ exerts protective effect against several neurotoxins in neuronal cell preparations. Here we examPalabras claves:Autores:Alvira D., Antoni Camins, Folch J., Pallás M., Rimbau V., Tajes M., Verdaguer E., Yeste M.Fuentes:scopusEvaluation of pathways involved in pentachlorophenol-induced apoptosis in rat neurons
ArticleAbstract: Pentachlorophenol (PCP) (C6HCl5O) is a synthetic toxic organochloride fungicide for humans which exhPalabras claves:Acute toxicity, apoptosis, caspase, cell cycle, Cerebellar granule neurons, Oxidative Stress, PentachlorophenolAutores:Alvira D., Antoni Camins, Bordas M., de la Torre A.V., Folch J., López-Querol M., Pallás M., Rimbau V., Sureda F.X., Yeste-Velasco M.Fuentes:scopusEvaluation of transcriptional activity of caspase-3 gene as a marker of acute neurotoxicity in rat cerebellar granular cells
ArticleAbstract: Caspase-3 is a key protein involved in the classical apoptosis mechanism in neurons, as in many othePalabras claves:Acute toxicity, apoptosis, Caspase-3, Cell-cycle, Cerebellar granule neurons, Oxidative StressAutores:Alvira D., Antoni Camins, Folch J., Forsby A., López-Querol M., Pallás M., Rimbau V., Sureda F.X., Tajes M.Fuentes:scopusNeuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the ATM/p53/E2F-1 path in cerebellar granule neurons
ArticleAbstract: The aim of the present study was to evaluate the neuroprotective effects of caffeine, an inhibitor oPalabras claves:Ataxia telangiectasia mutated, caffeine, Cerebellar granule cells, Complex I inhibition, E2F-1, MPP +Autores:Alvira D., Antoni Camins, Casadesús G., Folch J., Pallás M., Smith M.A., Yeste-Velasco M.Fuentes:scopusInhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons
ArticleAbstract: The biochemical pathways involved in neuronal cell death in Parkinson's disease are not completely cPalabras claves:apoptosis, Cerebellar granule cells, Cyclin dependent kinases, flavopiridol, Vitamin EAutores:Allgaier C., Alvira D., Antoni Camins, de Arriba S.G., Jiménez A., Matute C., Pallás M., Tajes M., Trullàs R., Verdaguer E.Fuentes:scopusInhibition of multiple pathways accounts for the antiapoptotic effects of flavopiridol on potassium withdrawal-induced apoptosis in neurons
ArticleAbstract: Serum and potassium (S/K) deprivation is a well-known apoptotic model in cerebellar granule neuronsPalabras claves:apoptosis, Cdk, cell cycle, flavopiridol, GSK-3β, MEF2Autores:Alvira D., Antoni Camins, Canudas A.M., Folch J., Jiménez A., Jordá E.G., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopus