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Acute Cocaine Enhances Dopamine D<inf>2</inf>R Recognition and Signaling and Counteracts D<inf>2</inf>R Internalization in Sigma1R-D<inf>2</inf>R Heteroreceptor Complexes
ArticleAbstract: The current study was performed to establish the actions of nanomolar concentrations of cocaine, notPalabras claves:Cocaine, dimerization, dopamine D2 receptor, Heteroreceptor complexes, Oligomerization, Sigma 1 receptor, Substance use disorderAutores:Beggiato S., Borroto-Escuela D.O., Ferraro L., Filip M., Fuxe K., Narváez M., Pinton L., Tanganelli S., W. Romero-Fernandez, Wydra K.Fuentes:scopusDopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers
ArticleAbstract: Biochemical, histochemical and coimmunoprecipitation experiments have indicated the existence of antPalabras claves:allosteric modulation, Dopamine D R receptor 2, G protein-coupled receptors, Heteromerization, Neurotensin 1 receptor, protein-protein interactionsAutores:Agnati L.F., Borroto-Escuela D.O., Brito I., Corrales F., Ferraro L., Fuxe K., Narváez M., Ravani A., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusMuscarinic receptor family interacting proteins: Role in receptor function
ArticleAbstract: G protein-coupled receptors constitute one of the most important families of membrane receptors throPalabras claves:G protein coupled receptors, Interacting proteins, Muscarinic receptors, Signal network, tandem affinity purificationAutores:Borroto-Escuela D.O., Ciruela F., Correia P.A., Fuxe K., Garriga P., Narváez M., W. Romero-FernandezFuentes:scopusHallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes
ArticleAbstract: Dopamine D2LR-serotonin 5-HT2AR heteromers were demonstrated in HEK293 cells after cotransfection ofPalabras claves:2,5-Dimethoxy-4-iodoamphetamine, allosteric modulation, Antipsychotic drugs, dopamine D2 receptor, G-protein-coupled receptors, Heterodimerization, Heteroreceptor complexes, Lysergic acid diethylamide, Receptor-receptor interactions, Serotonin 5-HT2A receptorAutores:Agnati L.F., Borroto-Escuela D.O., Fuxe K., Narváez M., Oflijan J., W. Romero-FernandezFuentes:scopusOn the existence and function of galanin receptor heteromers in the central nervous system
ReviewAbstract: Galanin receptor (GalR) subtypes 1-3 linked to central galanin neurons may form het- eromers with eaPalabras claves:5ht1a, Allosteric modulator, Galanin receptors, Gpcrs, Heteromers, NPY receptorsAutores:Agnati L.F., Borroto-Escuela D.O., Calvo F., Ciruela F., Díaz-Cabiale Z., Fuxe K., Garriga P., Millón C., Narvaez J.A., Narváez M., Parrado C., Tarakanov A.O., Tena M., W. Romero-FernandezFuentes:scopusReceptor–receptor interactions in multiple 5-HT1A heteroreceptor complexes in raphe-hippocampal 5-HT transmission and their relevance for depression and its treatment
ReviewAbstract: Due to the binding to a number of proteins to the receptor protomers in receptor heteromers in the bPalabras claves:Depression, Fibroblast growth factor receptor, G protein-coupled receptors, Galanin, Heteroreceptor complexes, Oligomerization, Receptor tyrosine kinase, Receptor-receptor interactions, Serotonin 5-HT1A receptorAutores:Ambrogini P., Andrade-Talavera Y., Borroto-Escuela D.O., Brito I., Díaz-Cabiale Z., Ferraro L., Flores-Burgess A., Fuxe K., Gago B., Millón C., Narvaez J.A., Narváez M., Odagaki Y., Palkovits M., W. Romero-FernandezFuentes:scopusThe existence of FGFR1-5-HT1A receptor heterocomplexes in midbrain 5-HT neurons of the rat: Relevance for neuroplasticity
ArticleAbstract: The ascending midbrain 5-HT neurons to the forebrain may be dysregulated in depression and have a rePalabras claves:Autores:Agnati L.F., Belluardo N., Borroto-Escuela D.O., Ciruela F., Fuxe K., Mudó G., Narváez M., Pérez-Alea M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusThe mGlu<inf>5</inf> Receptor Protomer-Mediated Dopamine D<inf>2</inf> Receptor Trans-Inhibition Is Dependent on the Adenosine A<inf>2A</inf> Receptor Protomer: Implications for Parkinson’s Disease
ArticleAbstract: The adenosine A2A receptor (A2AR), dopamine D2 receptor (D2R) and metabotropic glutamate receptor tyPalabras claves:Adenosine A receptor 2A, allosteric modulation, Dopamine D receptor 2, Heteroreceptor complex, Metabotropic glutamate receptor 5, Receptor-receptor interactionAutores:Borroto-Escuela D.O., Carlsson J., Ciruela F., Crans R.A.J., Fores-Pons R., Fuxe K., Lopez-Cano M., Narváez M., Taura J.J., W. Romero-FernandezFuentes:scopus