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Acta Paediatrica Scandinavica, Supplement(1)
Acta Paediatrica, International Journal of Paediatrics, Supplement(1)
Acta paediatrica (Oslo, Norway : 1992). Supplement(1)
Aging Cell(1)
Cell Metabolism(1)
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Enfermedades(6)
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scopus(8)
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
ArticleAbstract: Mutations in growth signaling pathways extend life span, as well as protect against age-dependent DNPalabras claves:Autores:Balasubramanian P., Cheng C.W., Cohen P., De Cabo R., Hwang D., Ingles S., Jaime Guevara-Aguirre, Longo V.D., Madia F., Marco Guevara-Aguirre, Martin-Montalvo A., Saavedra J., Wei M.Fuentes:scopusHormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/Laron syndrome
ArticleAbstract: Profound growth failure despite elevated GH levels in GH receptor deficiency (GHRD) results from redPalabras claves:Autores:Cohen P., Diamond F.B., Fielder P.J., Gargosky S.E., Jaime Guevara-Aguirre, Rosenbloom A.L., Rosenfeld R.G., Vaccarello M.A., Wilson K.F.Fuentes:scopusIGF-I regulates the age-dependent signaling peptide humanin
ArticleAbstract: Aging is influenced by endocrine pathways including the growth hormone/insulin-like growth factor-1Palabras claves:aging, Growth hormone, Humanin, IGF-I, longevityAutores:Bartke A., Cohen P., Fang Y., Jaime Guevara-Aguirre, Lee C., Longo V.D., Miyazaki B., Wan J., Yen K.Fuentes:scopusLow protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population
ArticleAbstract: Mice and humans with growth hormone receptor/IGF-1 deficiencies display major reductions in age-relaPalabras claves:Autores:Balasubramanian P., Brandhorst S., Cheng C.W., Cohen P., Crimmins E.M., Fontana L., Jaime Guevara-Aguirre, Kennedy B.K., Levine M.E., Longo V.D., Madia F., Mirisola M.G., Passarino G., Suarez J.A., Wan J., Wei M.Fuentes:scopusLong-term effects of insulin-like growth factor (IGF)-I treatment on serum IGFs and IGF binding proteins in adolescent patients with growth hormone receptor deficiency
ArticleAbstract: Objective. The aim of this investigation was to study the effect of relatively high dose IGF-I theraPalabras claves:Autores:Cohen P., Fielder P.J., Jaime Guevara-Aguirre, Martinez A.L., Martinez V., Rosenbloom A.L., Rosenfeld R.G., Vasconez O., Wilson K.F.Fuentes:scopusSerum levels of insulin-like growth factor binding proteins in Ecuadorean children with growth hormone insensitivity
Conference ObjectAbstract: Although insulin-like growth factor binding proteins (IGFBPs) are known to be important modulators oPalabras claves:Growth hormone, Growth hormone insensitivity, Insulin-like growth factor binding protein, Insulin-like growth factor IAutores:Burren C.P., Cohen P., Jaime Guevara-Aguirre, Mohan S., Rosenfeld R.G., Wanek D.Fuentes:scopusSerum profiles of insulin-like growth factors and their binding proteins in adults with growth hormone receptor deficiency treated with insulin-like growth factor I.
ArticleAbstract: Six adult patients with growth hormone receptor deficiency (GHRD) (2 men, 4 women) with an identicalPalabras claves:Autores:Cohen P., Diamond F.B., Fielder P.J., Gargosky S.E., Jaime Guevara-Aguirre, Rosenbloom A.L., Rosenfeld R.G., Vaccarello M.A., Wilson K.F.Fuentes:scopusRegulation of serum insulin-like growth factors and their binding proteins in Ecuadorean patients with growth hormone receptor dysfunction (growth hormone insensitivity)
Conference ObjectAbstract: Regulation of serum insulin-like growth factors (IGFs), IGF binding proteins (IGFBPs), and growth hoPalabras claves:Growth hormone binding protein Insulin-like growth factors, Growth hormone insensitivity, Heterozygotes, Insulin-like growth factors binding proteinsAutores:Cohen P., Fielder P.J., Hintz Rosenfeld R.L.R.G., Jaime Guevara-Aguirre, Rosenbloom A.L.Fuentes:scopus