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Apremilast microemulsion as topical therapy for local inflammation: Design, characterization and efficacy evaluation
ArticleAbstract: Apremilast (APR) is a selective phosphodiesterase 4 inhibitor administered orally in the treatment oPalabras claves:Apremilast, inflammation, Microemulsion, Phosphodiesterase 4, Skin DiseasesAutores:Badia J., Calpena A.C., Díaz-Garrido N., Fábrega M.J., Halbaut L., Lupe Carolina Espinoza, Paulo Sarango-Granda, Rodríguez-Lagunas M.J., Silva-Abreu M.Fuentes:scopusEnhanced transdermal delivery of pranoprofen using a thermo-reversible hydrogel loaded with lipid nanocarriers for the treatment of local inflammation
ArticleAbstract: A biocompatible topical thermo-reversible hydrogel containing Pranoprofen (PF)-loaded nanostructuredPalabras claves:inflammation, nanostructured lipid carriers, Pranoprofen, Thermo-reversible hydrogel, Transdermal deliveryAutores:Calpena A.C., Colom H., Lupe Carolina Espinoza, Rincón M., Rodríguez-Lagunas M.J., Silva-Abreu M., Sosa L.Fuentes:scopusQuality by Design of Pranoprofen Loaded Nanostructured Lipid Carriers and Their Ex Vivo Evaluation in Different Mucosae and Ocular Tissues
ArticleAbstract: Transmucosal delivery is commonly used to prevent or treat local diseases. Pranoprofen is an anti-inPalabras claves:design of experiment, nanostructured lipid carriers, ophthalmic tissues, permeation, porcine mucous membraneAutores:Abrego G., Calpena A.C., Lupe Carolina Espinoza, Mallandrich M., Pesantez-Narvaez J., Rincón M., Silva-Abreu M., Sosa L.Fuentes:scopus