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Fisiología y materias afines(2)
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Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism
ArticleAbstract: Palmitic acid (PA) is significantly increased in the hypothalamus of mice, when fed chronically withPalabras claves:Autores:Ávalos Y., Batista-Gonzalez A., Bertocchi C., Budini M., Burgos P., Burgos P.V., Cerda M., Cifuentes-Araneda F., Criollo A., Díaz-Castro F., Hernández-Cáceres M.P., Jasson A. Espinoza-Caicedo, Joy-Immediato M., Kretschmar C., Lagos P., Lopez-Gallardo E., Morselli E., Parra V., Perez-Leighton C., Pinto-Nuñez D., Rivera P., Rodriguez-Peña M., Toledo-Valenzuela L., Troncoso R., Venegas-Zamora L.Fuentes:scopusPalmitic acid reduces the autophagic flux and insulin sensitivity through the activation of the free fatty acid receptor 1 (FFAR1) in the hypothalamic neuronal cell line N43/5
ArticleAbstract: Chronic consumption of high fat diets (HFDs), rich in saturated fatty acids (SatFAs) like palmitic aPalabras claves:Akt, Autophagy, Central nervous system, G-protein coupled receptor 40, Glucose uptake, Insulin Resistance, Saturated fatty acidsAutores:Ávalos Y., Burgos P., Cifuentes-Araneda F., Criollo A., Díaz-Castro F., Hernández-Cáceres M.P., Jasson A. Espinoza-Caicedo, Morselli E., Narro C., Navarro-Aguad F., Peña-Oyarzun D., Riquelme C., Toledo-Valenzuela L., Troncoso R.Fuentes:scopus