Mostrando 2 resultados de: 2
Filtros aplicados
Origen
scopus(2)
A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone
ArticleAbstract: Abiraterone acetate is a potent inhibitor of human cytochrome P450c17 (CYP17A1, 17α-hydroxylase/17,2Palabras claves:abiraterone, androgen, CYP17A1, Cytochrome p450, Enzymology, Prostate cancer, steroidogenesisAutores:Bratoeff E., Garrido M., Peng H.M., Richard J. Auchus, Upadhyay S.K., Yoshimoto F.K.Fuentes:scopusThe diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1)
ReviewAbstract: The steroid hydroxylation and carbon–carbon bond cleavage activities of cytochrome P450 17A1 (CYP17APalabras claves:17,20-Lyase, 17-Hydroxylase, androgen, Cytochrome p450, Hypertension, Metabolic switching, steroidogenesisAutores:Richard J. Auchus, Yoshimoto F.K.Fuentes:scopus