Mostrando 2 resultados de: 2
A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone
ArticleAbstract: Abiraterone acetate is a potent inhibitor of human cytochrome P450c17 (CYP17A1, 17α-hydroxylase/17,2Palabras claves:abiraterone, androgen, CYP17A1, Cytochrome p450, Enzymology, Prostate cancer, steroidogenesisAutores:Bratoeff E., Garrido M., Peng H.M., Richard J. Auchus, Upadhyay S.K., Yoshimoto F.K.Fuentes:scopusEpoxidation activities of human cytochromes P450c17 and P450c21
ArticleAbstract: Some cytochrome P450 enzymes epoxidize unsaturated substrates, but this activity has not been descriPalabras claves:Autores:Anderson S.M., Peng H.M., Richard J. Auchus, Yoshimoto F.K., Zhang H.Fuentes:scopus