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Human cytochrome P450 21A2, the major steroid 21-hydroxylase: Structure of the enzyme•progesterone substrate complex and rate-limiting C-H bond cleavage
ArticleAbstract: Cytochrome P450 (P450) 21A2 is the major steroid 21-hydroxylase, and deficiency of this enzyme is inPalabras claves:Autores:Egli M., Guengerich F.P., Lei L., Pallan P.S., Richard J. Auchus, Wang C., Waterman M.R., Yoshimoto F.K.Fuentes:scopusThe diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1)
ReviewAbstract: The steroid hydroxylation and carbon–carbon bond cleavage activities of cytochrome P450 17A1 (CYP17APalabras claves:17,20-Lyase, 17-Hydroxylase, androgen, Cytochrome p450, Hypertension, Metabolic switching, steroidogenesisAutores:Richard J. Auchus, Yoshimoto F.K.Fuentes:scopus