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scopus(3)
Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors
ArticleAbstract: Neglected tropical diseases caused by parasitic infections are an ongoing and increasing concern. ThPalabras claves:Drug Discovery, natural product analogues, trypanosomatids, [3+2] cycloadditionAutores:Florence G.J., Fraser A.L., Gould E.R., King E.F.B., Morris J.C., Smith T.K., Stefanie K. Menzies, Thomson M.I., Tulloch L.B., Zacharova M.K.Fuentes:scopusPhoto-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues
ArticleAbstract: Current drugs to treat African sleeping sickness are inadequate and new therapies are urgently requiPalabras claves:Autores:Florence G.J., Fraser A.L., Gould E.R., King E.F.B., Smith T.K., Stefanie K. Menzies, Tulloch L.B., Zacharova M.K.Fuentes:scopusSimplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins
ArticleAbstract: The need for new treatments for the neglected tropical diseases African sleeping sickness, Chagas diPalabras claves:Acetogenins, Natural products, neglected tropical diseases, TetrahydropyranAutores:Florence G.J., Fraser A.L., Gould E.R., King E.F.B., Smith T.K., Stefanie K. Menzies, Tulloch L.B., Zacharova M.K.Fuentes:scopus