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Effect of a new series of synthetic spiroteroids on the PC12 cell line viability
ArticleAbstract: Introduction: diosgenin and its derivatives have been described as potent anti-proliferative compounPalabras claves:Cytotoxicity, Spirosteroids, Structure-activity relationship, Taurodeoxycholic acidAutores:García-Pupo L., Juan Enrique Tacoronte-Morales, Núñez-Figueredo Y., René D.H.Fuentes:scopusThe anti-cancer agent guttiferone-A permeabilizes mitochondrial membrane: Ensuing energetic and oxidative stress implications
ArticleAbstract: Guttiferone-A (GA) is a natural occurring polyisoprenylated benzophenone with cytotoxic action in viPalabras claves:Anti-cancer action, Guttiferone-A, HepG2 cells, Mitochondria, Mitochondrial membrane permeabilization, Oxidative Stress, UncouplingAutores:Alberici L.C., Curti C., Leopoldino A.M., Núñez-Figueredo Y., Osmany Cuesta-Rubio, Pardo-Andreu G.L., Pestana C.R., Rodrigues F.P., Tudella V.G., Uyemura S.A.Fuentes:googlescopus