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C-Phycocyanin ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells
ArticleAbstract: For decades Experimental Autoimmune Encephalitis (EAE) has remained as an unsurpassed multiple sclerPalabras claves:Central nervous system, Demyelination, Multiple Sclerosis, Neurodegenerative disorder, Regulatory T cellsAutores:Acosta-Medina E.F., Alexey Llópiz-Arzuaga, Alonso-Ramírez R., Cervantes-Llanos M., Falcón-Cama V., Guillén-Nieto G.E., Lagumersindez-Denis N., López-Saura P.A., Marín-Prida J., Martínez-Sánchez G., Pentón-Arias E., Pentón-Rol G., Rodríguez-Jiménez E., Valenzuela-Silva C.M.Fuentes:googlescopusC-Phycocyanin is neuroprotective against global cerebral ischemia/reperfusion injury in gerbils
ArticleAbstract: Although the huge economic and social impact and the pbkp_redicted incidence increase, neuroprotectiPalabras claves:antioxidant, C-Phycocyanin, Gerbil, Global cerebral ischemia/reperfusion, neuroprotectionAutores:Acosta-Medina E.F., Alexey Llópiz-Arzuaga, Guillén-Nieto G.E., Lagumersindez-Denis N., López-Saura P.A., Marín-Prida J., Martínez-Sánchez G., Pardo-Andreu G.L., Pentón-Arias E., Pentón-Rol G., Rodríguez-Jiménez E., Valdivia-Acosta A.Fuentes:googlescopusA modified variant of human Interleukin-15 as a novel antigen for active immunotherapy in rheumatoid arthritis
ReviewAbstract: Interleukin (IL)-15 is a pro-inflammatory cytokine that plays a crucial role in the pathogenesis ofPalabras claves:IL-15, Immunization, neutralizing antibodies, non-human primates, Rheumatoid ArthritisAutores:Alexey Llópiz-Arzuaga, Arrieta C.A., Besada-Pérez V., Castro-Velazco J., Eugenio Hardy, Geronimo H., Guillén-Nieto G.E., Martínez K., Martínez-Castillo R., Morera-Díaz Y., Moro A., Perea-Rodríguez S.E., Puente P., Ramos Y., Rodríguez-Álvarez Y., Santos-Savio A., Silva R., Vázquez M.Fuentes:scopusA novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: Report of a pilot clinical trial
ArticleAbstract: Background: There is evidence of a relationship between epidermal growth factor (EGF) and tumor cellPalabras claves:cancer vaccine, Epidermal growth factorAutores:Catala M., González G., Gonzalez Y.S., Guillén-Nieto G.E., Hernández J.C., Lage Davila A., Marinello P., Mirabal V., Tania CrombetFuentes:scopusGene therapy using a plasmid that expresses the VEGF<inf>121</inf> for the treatment of the critical ischemic cardiophaty
ArticleAbstract: Here we report, for the first time in Cuba, the use of gene therapy to evaluate the positive therapePalabras claves:Clinical study, Gene therapy, Vascular endothelial growth factorAutores:Batista J.F., Betancourt B.Y., Chaos N., Chil R., Coca M., Fleites G., García A., García E., Garzón E., González M.J., González N., González R., Guevara L., Guillén-Nieto G.E., Méndez T., Milán R., Naffe M., Quián Y.P., Reina C., Santiago Nelson Vispo, Senra G., Seralena A., Suárez L.R., Vazquez R., Villar A.Fuentes:scopusGene therapy with a plasmid expressing the VEGF<inf>121</inf> for the treatment of critical ischemic cardiopathy
ArticleAbstract: Here we report, for the first time in Cuba, the evaluation of the positive therapeutic action and saPalabras claves:Autores:Batista J.F., Betancourt B.Y., Chaos N., Chil R., Coca M., Fleites G., García A., García E., Garzón E., González M.J., González N., González R., Guevara L., Guillén-Nieto G.E., Méndez T., Milán R., Naffe M., Quián Y.P., Reina C., Santiago Nelson Vispo, Senra G., Seralena A., Suárez L.R., Vazquez R., Villar A.Fuentes:scopusExpression in Escherichia coli of the IpdA gene, protein sequence analysis and immunological characterization of the P64k protein from Neisseria meningitidis
ArticleAbstract: By making use of recombinant DNA technology it is possible to characterize meningococcal outer membrPalabras claves:Autores:Alvarez A., Besada-Pérez V., Caballero E., Carmenate T., Coizeau E., Estrada R., González L.J., González S., Guillén-Nieto G.E., Herrera L., Musacchio Lasa A., Nazabal C., Padrón G., Silva R., Támbara Y., Vivian Morera CórdovaFuentes:scopusGrowth Hormone Releasing Peptide 6 (GHRP6) reduces liver fibrosis in CCl4 chronically intoxicated rats
ArticleAbstract: Tissue fibrosis is a leading cause of morbidity and mortality. Current treatments for conditions sucPalabras claves:Carbon tetrachloride, Cirrhosis, Cytoprotection, FIBROSIS, GHRP6, Liver, SecretagogueAutores:Abreu A., Berlanga-Acosta J., Bringas R., Cibrín D., Cintado A., Coro-Antich R., Cosme-Díz K., Cruz Y., Fernández-Massó J.R., García-del Barco D., González-Ferrer Y., Guillén I., Guillén-Nieto G.E., I. Howland-Álvarez, Inés L., Ivón Howland-Álvarez, León-Fernández O.S., López-Mola E., Mendoza-Marí Y., Miranda J., Nazabal M., Ochagavía M.E., Palenzuela D., Suaréz J., Ugarte-Moreno D., Vázquez-Blomquist D., Vila J.M.Fuentes:googlescopusGrowth-hormone-releasing peptide 6 (GHRP6) prevents oxidant cytotoxicity and reduces myocardial necrosis in a model of acute myocardial infarction
ArticleAbstract: Therapies aimed at enhancing cardiomyocyte survival following myocardial injury are urgently requirePalabras claves:Cardioprotection, Growth-hormone-releasing peptide 6 (GHRP6), infarction, Ischaemia, myocardium, Necrosis, Oxidative StressAutores:Alba J., Berlanga-Acosta J., Cibrian D., Dominguez H., Garcia D., Guevara L., Guillén-Nieto G.E., López-Mola E., López-Saura P.A., Perez B., Rodriguez A., Santiago Nelson Vispo, Seralena A.Fuentes:scopusOpen letter to president Biden about COVID vaccines for Cuba
OtherAbstract:Palabras claves:Autores:García D., Guillén-Nieto G.E., Herrera L., Lage Davila A., Mauri M., Pérez R., Tania Crombet, Valdés-Sosa M., Valdés-Sosa P., Vérez V.Fuentes:scopus