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A modified variant of human Interleukin-15 as a novel antigen for active immunotherapy in rheumatoid arthritis
ReviewAbstract: Interleukin (IL)-15 is a pro-inflammatory cytokine that plays a crucial role in the pathogenesis ofPalabras claves:IL-15, Immunization, neutralizing antibodies, non-human primates, Rheumatoid ArthritisAutores:Alexey Llópiz-Arzuaga, Arrieta C.A., Besada-Pérez V., Castro-Velazco J., Eugenio Hardy, Geronimo H., Guillén-Nieto G.E., Martínez K., Martínez-Castillo R., Morera-Díaz Y., Moro A., Perea-Rodríguez S.E., Puente P., Ramos Y., Rodríguez-Álvarez Y., Santos-Savio A., Silva R., Vázquez M.Fuentes:scopusGene therapy using a plasmid that expresses the VEGF<inf>121</inf> for the treatment of the critical ischemic cardiophaty
ArticleAbstract: Here we report, for the first time in Cuba, the use of gene therapy to evaluate the positive therapePalabras claves:Clinical study, Gene therapy, Vascular endothelial growth factorAutores:Batista J.F., Betancourt B.Y., Chaos N., Chil R., Coca M., Fleites G., García A., García E., Garzón E., González M.J., González N., González R., Guevara L., Guillén-Nieto G.E., Méndez T., Milán R., Naffe M., Quián Y.P., Reina C., Santiago Nelson Vispo, Senra G., Seralena A., Suárez L.R., Vazquez R., Villar A.Fuentes:scopusGene therapy with a plasmid expressing the VEGF<inf>121</inf> for the treatment of critical ischemic cardiopathy
ArticleAbstract: Here we report, for the first time in Cuba, the evaluation of the positive therapeutic action and saPalabras claves:Autores:Batista J.F., Betancourt B.Y., Chaos N., Chil R., Coca M., Fleites G., García A., García E., Garzón E., González M.J., González N., González R., Guevara L., Guillén-Nieto G.E., Méndez T., Milán R., Naffe M., Quián Y.P., Reina C., Santiago Nelson Vispo, Senra G., Seralena A., Suárez L.R., Vazquez R., Villar A.Fuentes:scopusGrowth Hormone Releasing Peptide 6 (GHRP6) reduces liver fibrosis in CCl4 chronically intoxicated rats
ArticleAbstract: Tissue fibrosis is a leading cause of morbidity and mortality. Current treatments for conditions sucPalabras claves:Carbon tetrachloride, Cirrhosis, Cytoprotection, FIBROSIS, GHRP6, Liver, SecretagogueAutores:Abreu A., Berlanga-Acosta J., Bringas R., Cibrín D., Cintado A., Coro-Antich R., Cosme-Díz K., Cruz Y., Fernández-Massó J.R., García-del Barco D., González-Ferrer Y., Guillén I., Guillén-Nieto G.E., I. Howland-Álvarez, Inés L., Ivón Howland-Álvarez, León-Fernández O.S., López-Mola E., Mendoza-Marí Y., Miranda J., Nazabal M., Ochagavía M.E., Palenzuela D., Suaréz J., Ugarte-Moreno D., Vázquez-Blomquist D., Vila J.M.Fuentes:googlescopusIdentification of the first antagonist peptide that inhibits biological effects of interleukin-15
ArticleAbstract: Interleukin-15 (IL-15) is a pro-inflammatory cytokine that is expressed in several autoimmune and inPalabras claves:Alpha receptor, antagonist, Cytokine, IL-15, peptideAutores:Alexey Llópiz-Arzuaga, Altruda F., Ancisar J.A., Arrieta C.A., Cabrales A., Chico A., Estévez M., Garay H.E., Geronimo H., Guillén-Nieto G.E., Machado A.C., Noda J., Ojeda M., Perea-Rodríguez S.E., Reyes O., Rodríguez-Álvarez Y., Sánchez A., Santos-Savio A., Silengo L., Suaréz J., Vázquez M.Fuentes:googlescopusProtective immune response against Neisseria meningitidis serogroup B after immunization with peptides mimicking a capsular polysaccharide epitope
ArticleAbstract:Palabras claves:Autores:Brown E., Caballero E., Carmenate T., Chinea G., Cobas K., Coizeau E., Cruz Y., Garay H.E., González S., Guillén-Nieto G.E., Martín A., Menéndez T., Noda J., Reyes O., Santiago Nelson Vispo, Soria Y., Vivian Morera Córdova, Yero D.Fuentes:scopus