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Chronic lymphocytic leukemia with proliferation centers in bone marrow is associated with younger age at initial presentation, complex karyotype, and TP53 disruption
ArticleAbstract: The presence of expanded proliferation centers (PCs) in lymph nodes involved by chronic lymphocyticPalabras claves:Bone marrow, Chronic lymphocytic leukemia/small lymphocytic lymphoma, Complex karyotype, Proliferation centers, TP53Autores:Bueso-Ramos C., Hu S., Kanagal-Shamanna R., Khoury J.D., Loghavi S., Luthra R., Medeiros L.J., Ok C.Y., Patel K.P., Routbort M.J., Salem A., Schlette E., Sofía A. Garcés, Tang G., Wang S.A.Fuentes:scopusCyclin D1 expression in Rosai-Dorfman disease: a near-constant finding that is not invariably associated with mitogen-activated protein kinase/extracellular signal–regulated kinase pathway activation
ArticleAbstract: Activating mutations in the mitogen-activated protein kinase/extracellular signal–regulated kinase (Palabras claves:BCL-2, Cyclin D1, Ki-67, MAPK/ERK, p-ERK, pathogenesis, Rosai-dorfman diseaseAutores:Bhattacharjee M.B., Coelho Siqueira S.A., Cuglievan B., Garces J.C., Jelloul F.Z., Khoury J.D., Li S., Marques-Piubelli M.L., Medeiros L.J., Medina A.M., Miranda R.N., Saluja K., Sofía A. Garcés, Sriganeshan V., Thakral B., Xu J., Yin C.C.Fuentes:scopus