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Biotecnologia Aplicada(1)
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PEGylated interferon-α2b: A branched 40K polyethylene glycol derivative
ArticleAbstract: Purpose. The conjugation of interferon-α2b (IFN-α2b) to a branched-chain (40,000) polyethylene glycoPalabras claves:Branched chain PEG, IFN-α2b, In vitro stability, Pegylation, pharmacokineticsAutores:Aldana R., Báez R., Eugenio Hardy, Ramon J., Saez V.Fuentes:scopusMicroencapsulation of recombinant interferon α-2b into poly (D,L-lactide-co-glycolide) microspheres
ArticleAbstract: Interferon-aαb (IFN-α2b) produced in Cuba by the Center for Genetic Engineering and Biotechnology waPalabras claves:Controlled release, INTERFERÓN, Microspheres, Poly (lactide-co-glycolide), Protein deliveryAutores:Aldana R., Eugenio Hardy, Pérez D., Ramon J., Saez V.Fuentes:scopusLong-term of a new freeze-dried and albumin-free formulation of recombinant human interferon alpha 2b
ArticleAbstract: In this work, we evaluate the stability of a new freeze-dried and albumin-free formulation of recombPalabras claves:Albumin-free formulation, Freeze-dried formulation, INTERFERÓN, stabilityAutores:Aldana R., Aroche K., Báez R., Eugenio Hardy, Reyes N., Ruiz L., Sotolongo J.Fuentes:scopusSome factors affecting the stability of interferon alpha 2b in solution
ArticleAbstract: In this paper we evaluated the influence of the protein concentration and a formulation vehicle on tPalabras claves:Albumin-free formulation, INTERFERÓN, Protein concentration, stabilityAutores:Aldana R., Aroche K., Báez R., Eugenio Hardy, Reyes N., Ruiz L.Fuentes:scopus